KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF38A
All Species:
41.82
Human Site:
Y98
Identified Species:
76.67
UniProt:
Q8NAV1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAV1
NP_116253.2
312
37477
Y98
I
K
N
E
D
F
K
Y
V
R
M
L
G
A
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111695
312
37444
Y98
I
K
N
E
D
F
K
Y
V
R
M
L
G
A
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q4FK66
312
37418
Y98
I
K
N
E
D
F
K
Y
V
R
M
L
G
A
L
Rat
Rattus norvegicus
Q6AXY7
542
63914
Y156
I
T
H
T
D
S
P
Y
I
R
A
L
G
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234245
312
37442
Y98
I
K
N
E
D
F
K
Y
V
R
M
L
G
A
L
Frog
Xenopus laevis
Q4FZQ6
312
37276
Y98
I
K
N
E
D
F
K
Y
V
R
A
L
G
A
L
Zebra Danio
Brachydanio rerio
Q6DHU4
313
37532
Y98
I
K
N
E
D
F
K
Y
V
R
L
L
G
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610463
330
40069
Y98
I
K
N
E
E
F
K
Y
V
R
A
L
G
A
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23121
312
35023
G102
S
Y
S
G
G
G
G
G
G
R
D
R
F
D
R
Sea Urchin
Strong. purpuratus
XP_781290
318
36969
Y98
I
K
N
E
D
F
K
Y
V
R
C
L
G
A
L
Poplar Tree
Populus trichocarpa
XP_002319497
297
35725
F90
E
K
D
I
V
V
E
F
I
K
N
E
D
Y
K
Maize
Zea mays
NP_001151258
389
46781
Y98
I
K
N
E
D
Y
K
Y
V
R
V
L
G
A
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565937
355
43154
Y98
I
K
N
D
D
Y
K
Y
V
R
I
L
G
A
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
N.A.
N.A.
98.7
23.6
N.A.
N.A.
97.7
91.6
88.5
N.A.
53.6
N.A.
20.5
51.2
Protein Similarity:
100
N.A.
99.6
N.A.
N.A.
99
35.6
N.A.
N.A.
99
96.7
96.1
N.A.
67.5
N.A.
33.9
64.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
40
N.A.
N.A.
100
93.3
86.6
N.A.
80
N.A.
6.6
93.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
60
N.A.
N.A.
100
93.3
100
N.A.
86.6
N.A.
13.3
93.3
Percent
Protein Identity:
54.1
48.3
N.A.
47.3
N.A.
N.A.
Protein Similarity:
66.9
58.6
N.A.
62.5
N.A.
N.A.
P-Site Identity:
6.6
80
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
40
93.3
N.A.
93.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
24
0
0
77
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
8
77
0
0
0
0
0
8
0
8
8
0
% D
% Glu:
8
0
0
70
8
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
62
0
8
0
0
0
0
8
8
24
% F
% Gly:
0
0
0
8
8
8
8
8
8
0
0
0
85
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
85
0
0
8
0
0
0
0
16
0
8
0
0
0
0
% I
% Lys:
0
85
0
0
0
0
77
0
0
8
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
85
0
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
16
% M
% Asn:
0
0
77
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
93
0
8
0
0
8
% R
% Ser:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
8
0
0
77
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
16
0
85
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _