Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPF38A All Species: 30.91
Human Site: Y19 Identified Species: 56.67
UniProt: Q8NAV1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NAV1 NP_116253.2 312 37477 Y19 I H G T N P Q Y L V E K I I R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001111695 312 37444 Y19 I H G T N P Q Y L V E K I I R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q4FK66 312 37418 Y19 I H G T N P Q Y L V E K I I R
Rat Rattus norvegicus Q6AXY7 542 63914 M56 L W G N E K T M N L N P M I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234245 312 37442 Y19 I H G T N P Q Y L V E K I I R
Frog Xenopus laevis Q4FZQ6 312 37276 Y19 V H G T N P Q Y L V E K I I R
Zebra Danio Brachydanio rerio Q6DHU4 313 37532 Y19 V H G T N P Q Y L V E K I I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610463 330 40069 Y19 V H G T N P Q Y L I E K I I R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23121 312 35023 V32 G Y G Q I R D V L L K N G F G
Sea Urchin Strong. purpuratus XP_781290 318 36969 Y19 I K G K N P Q Y L V E K I T R
Poplar Tree Populus trichocarpa XP_002319497 297 35725 N19 I R G T N P Q N L V E K I L R
Maize Zea mays NP_001151258 389 46781 N19 I H G T N P Q N L V E K I V R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565937 355 43154 N19 I R G T N P Q N L V E K I V R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.6 N.A. N.A. 98.7 23.6 N.A. N.A. 97.7 91.6 88.5 N.A. 53.6 N.A. 20.5 51.2
Protein Similarity: 100 N.A. 99.6 N.A. N.A. 99 35.6 N.A. N.A. 99 96.7 96.1 N.A. 67.5 N.A. 33.9 64.4
P-Site Identity: 100 N.A. 100 N.A. N.A. 100 13.3 N.A. N.A. 100 93.3 93.3 N.A. 86.6 N.A. 13.3 80
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 33.3 N.A. N.A. 100 100 100 N.A. 100 N.A. 33.3 80
Percent
Protein Identity: 54.1 48.3 N.A. 47.3 N.A. N.A.
Protein Similarity: 66.9 58.6 N.A. 62.5 N.A. N.A.
P-Site Identity: 80 86.6 N.A. 80 N.A. N.A.
P-Site Similarity: 86.6 93.3 N.A. 86.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 85 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 0 100 0 0 0 0 0 0 0 0 0 8 0 8 % G
% His: 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 62 0 0 0 8 0 0 0 0 8 0 0 85 62 0 % I
% Lys: 0 8 0 8 0 8 0 0 0 0 8 85 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 93 16 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 8 85 0 0 24 8 0 8 8 0 0 0 % N
% Pro: 0 0 0 0 0 85 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 8 0 0 85 0 0 0 0 0 0 0 0 % Q
% Arg: 0 16 0 0 0 8 0 0 0 0 0 0 0 0 85 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 77 0 0 8 0 0 0 0 0 0 8 0 % T
% Val: 24 0 0 0 0 0 0 8 0 77 0 0 0 16 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 62 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _