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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF38A
All Species:
15.45
Human Site:
S243
Identified Species:
28.33
UniProt:
Q8NAV1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAV1
NP_116253.2
312
37477
S243
S
R
S
P
R
R
R
S
R
S
P
K
R
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111695
312
37444
S243
S
R
S
P
R
R
R
S
R
S
P
K
R
R
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q4FK66
312
37418
S243
S
R
S
P
R
R
R
S
R
S
P
K
R
R
S
Rat
Rattus norvegicus
Q6AXY7
542
63914
K401
S
R
G
E
G
E
E
K
K
H
K
E
D
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234245
312
37442
S243
S
R
S
P
R
R
R
S
R
S
P
K
R
R
S
Frog
Xenopus laevis
Q4FZQ6
312
37276
R243
R
S
P
R
R
R
S
R
S
P
K
R
R
S
P
Zebra Danio
Brachydanio rerio
Q6DHU4
313
37532
S243
S
P
R
R
R
S
R
S
P
K
R
R
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610463
330
40069
D243
G
N
S
A
R
S
R
D
Y
Y
D
E
L
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23121
312
35023
P242
K
S
R
S
R
S
P
P
K
R
S
R
R
E
S
Sea Urchin
Strong. purpuratus
XP_781290
318
36969
R243
Q
S
I
P
G
G
R
R
D
I
F
W
T
N
V
Poplar Tree
Populus trichocarpa
XP_002319497
297
35725
G229
L
R
D
E
R
D
Y
G
H
D
R
E
R
E
R
Maize
Zea mays
NP_001151258
389
46781
R243
N
R
D
K
D
Y
D
R
D
R
D
Y
D
R
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565937
355
43154
R263
G
H
G
R
D
R
D
R
E
R
D
R
D
H
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
N.A.
N.A.
98.7
23.6
N.A.
N.A.
97.7
91.6
88.5
N.A.
53.6
N.A.
20.5
51.2
Protein Similarity:
100
N.A.
99.6
N.A.
N.A.
99
35.6
N.A.
N.A.
99
96.7
96.1
N.A.
67.5
N.A.
33.9
64.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
13.3
N.A.
N.A.
100
20
33.3
N.A.
20
N.A.
20
13.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
33.3
N.A.
N.A.
100
26.6
40
N.A.
26.6
N.A.
33.3
13.3
Percent
Protein Identity:
54.1
48.3
N.A.
47.3
N.A.
N.A.
Protein Similarity:
66.9
58.6
N.A.
62.5
N.A.
N.A.
P-Site Identity:
20
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
20
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
16
8
16
8
16
8
24
0
24
0
16
% D
% Glu:
0
0
0
16
0
8
8
0
8
0
0
24
0
24
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
16
0
16
0
16
8
0
8
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
8
8
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
8
16
8
16
31
0
8
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
39
0
0
8
8
8
8
31
0
0
8
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
54
16
24
70
47
54
31
31
24
16
31
54
39
8
% R
% Ser:
47
24
39
8
0
24
8
39
8
31
8
0
8
8
47
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
8
8
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _