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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF38A
All Species:
13.94
Human Site:
S216
Identified Species:
25.56
UniProt:
Q8NAV1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NAV1
NP_116253.2
312
37477
S216
S
P
D
H
R
R
R
S
Y
R
D
L
D
K
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111695
312
37444
S216
S
P
D
H
R
R
R
S
Y
R
D
L
D
K
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q4FK66
312
37418
S216
S
P
D
H
R
R
R
S
Y
R
D
L
D
K
P
Rat
Rattus norvegicus
Q6AXY7
542
63914
R374
D
R
D
Y
D
K
D
R
G
N
D
R
E
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234245
312
37442
G216
S
P
D
H
R
R
R
G
Y
R
D
L
D
K
P
Frog
Xenopus laevis
Q4FZQ6
312
37276
Y216
P
E
H
H
R
R
N
Y
R
D
L
D
R
P
R
Zebra Danio
Brachydanio rerio
Q6DHU4
313
37532
S216
S
P
E
P
H
R
R
S
Y
R
D
M
D
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610463
330
40069
R216
S
T
A
V
R
R
P
R
R
V
R
S
K
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23121
312
35023
R215
S
R
S
N
S
R
S
R
S
R
S
R
S
R
D
Sea Urchin
Strong. purpuratus
XP_781290
318
36969
G216
S
C
W
L
L
I
K
G
Y
A
E
G
T
N
V
Poplar Tree
Populus trichocarpa
XP_002319497
297
35725
G202
E
E
N
E
Q
L
E
G
L
D
N
G
A
D
E
Maize
Zea mays
NP_001151258
389
46781
R216
E
N
D
N
H
R
G
R
S
L
A
R
E
R
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565937
355
43154
D236
S
H
R
H
R
D
R
D
Y
D
R
D
Y
D
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
N.A.
N.A.
98.7
23.6
N.A.
N.A.
97.7
91.6
88.5
N.A.
53.6
N.A.
20.5
51.2
Protein Similarity:
100
N.A.
99.6
N.A.
N.A.
99
35.6
N.A.
N.A.
99
96.7
96.1
N.A.
67.5
N.A.
33.9
64.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
13.3
N.A.
N.A.
93.3
20
66.6
N.A.
20
N.A.
20
13.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
40
N.A.
N.A.
93.3
20
86.6
N.A.
20
N.A.
33.3
26.6
Percent
Protein Identity:
54.1
48.3
N.A.
47.3
N.A.
N.A.
Protein Similarity:
66.9
58.6
N.A.
62.5
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
20
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
8
8
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
47
0
8
8
8
8
0
24
47
16
39
16
24
% D
% Glu:
16
16
8
8
0
0
8
0
0
0
8
0
16
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
24
8
0
0
16
0
0
0
% G
% His:
0
8
8
47
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
0
0
0
0
8
31
0
% K
% Leu:
0
0
0
8
8
8
0
0
8
8
8
31
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
8
8
16
0
0
8
0
0
8
8
0
0
8
0
% N
% Pro:
8
39
0
8
0
0
8
0
0
0
0
0
0
8
39
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
8
0
54
70
47
31
16
47
16
24
8
31
16
% R
% Ser:
70
0
8
0
8
0
8
31
16
0
8
8
8
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
54
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _