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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF4L2
All Species:
22.42
Human Site:
S275
Identified Species:
44.85
UniProt:
Q8NA75
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NA75
NP_689631.1
395
43747
S275
S
H
D
S
A
V
T
S
L
Q
I
L
Q
D
G
Chimpanzee
Pan troglodytes
XP_528183
395
43731
S275
S
H
D
S
A
V
T
S
L
Q
I
L
Q
D
G
Rhesus Macaque
Macaca mulatta
XP_001083861
395
43809
S275
S
H
D
S
A
V
T
S
L
Q
I
L
Q
E
G
Dog
Lupus familis
XP_547889
530
58560
S410
F
H
D
S
A
V
T
S
V
Q
I
L
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PE01
358
39257
S249
L
S
L
S
S
E
G
S
Y
L
L
S
N
A
M
Rat
Rattus norvegicus
NP_001102186
518
57947
S375
F
H
D
S
A
V
T
S
V
Q
V
F
K
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421173
500
56103
I381
H
D
S
A
V
T
S
I
R
L
L
E
A
E
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956995
505
56840
I370
R
F
Y
Q
E
S
A
I
T
S
V
Q
L
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785369
524
58817
S395
S
H
R
V
A
V
C
S
L
K
L
L
K
E
E
Poplar Tree
Populus trichocarpa
XP_002299385
471
52805
Y309
F
I
R
H
R
I
P
Y
S
S
L
G
R
Q
G
Maize
Zea mays
NP_001144864
497
53974
P339
S
N
A
R
R
T
V
P
M
L
P
T
R
H
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197239
467
51958
N332
L
F
L
Q
L
Q
G
N
I
N
P
S
H
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
96.1
56
N.A.
21.2
53.6
N.A.
N.A.
49.4
N.A.
43.3
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
100
98.9
98.7
64.3
N.A.
36.7
64.4
N.A.
N.A.
61
N.A.
56.8
N.A.
N.A.
N.A.
N.A.
42.9
P-Site Identity:
100
100
93.3
73.3
N.A.
13.3
53.3
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
26.6
80
N.A.
N.A.
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
20.5
21.9
N.A.
21.4
N.A.
N.A.
Protein Similarity:
38
35
N.A.
38.7
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
26.6
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
50
0
9
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
42
0
0
0
0
0
0
0
0
0
0
17
0
% D
% Glu:
0
0
0
0
9
9
0
0
0
0
0
9
0
42
25
% E
% Phe:
25
17
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
0
0
0
0
9
0
0
34
% G
% His:
9
50
0
9
0
0
0
0
0
0
0
0
9
9
9
% H
% Ile:
0
9
0
0
0
9
0
17
9
0
34
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% K
% Leu:
17
0
17
0
9
0
0
0
34
25
34
42
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
9
0
0
0
0
0
9
0
9
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
9
9
0
0
17
0
0
0
0
% P
% Gln:
0
0
0
17
0
9
0
0
0
42
0
9
34
9
9
% Q
% Arg:
9
0
17
9
17
0
0
0
9
0
0
0
17
0
9
% R
% Ser:
42
9
9
50
9
9
9
59
9
17
0
17
0
0
0
% S
% Thr:
0
0
0
0
0
17
42
0
9
0
0
9
0
0
0
% T
% Val:
0
0
0
9
9
50
9
0
17
0
17
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
9
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _