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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TC2N
All Species:
17.88
Human Site:
S325
Identified Species:
49.17
UniProt:
Q8N9U0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9U0
NP_001122067.1
490
55257
S325
K
K
T
I
G
E
C
S
M
S
L
R
T
L
S
Chimpanzee
Pan troglodytes
XP_001145068
490
55210
S325
K
K
T
I
G
E
C
S
L
S
L
R
T
L
S
Rhesus Macaque
Macaca mulatta
XP_001091431
490
55318
S325
K
K
T
I
G
K
C
S
L
S
L
R
T
L
S
Dog
Lupus familis
XP_547711
490
55373
S325
K
K
T
I
G
E
C
S
L
S
L
R
T
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91XT6
489
54996
L325
K
T
I
G
E
C
S
L
S
L
R
T
L
S
T
Rat
Rattus norvegicus
NP_001020323
489
55035
L325
K
T
I
G
E
C
S
L
S
L
R
T
L
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507084
490
54806
S325
K
K
T
I
G
E
C
S
L
S
L
R
E
L
S
Chicken
Gallus gallus
XP_421322
489
55212
L325
R
T
I
G
E
C
S
L
S
L
R
E
L
S
S
Frog
Xenopus laevis
NP_001088877
484
54129
L322
I
S
H
C
S
I
S
L
R
D
L
S
E
E
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
89.3
N.A.
87.7
86.7
N.A.
77.7
68.3
61
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.1
94.9
N.A.
92
91.4
N.A.
86.9
81.8
77.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
93.3
N.A.
6.6
6.6
N.A.
86.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
93.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
12
0
34
56
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
34
45
0
0
0
0
0
12
23
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
34
56
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
34
56
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
78
56
0
0
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
45
45
34
67
0
34
56
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
12
0
34
56
0
0
0
% R
% Ser:
0
12
0
0
12
0
45
56
34
56
0
12
0
34
67
% S
% Thr:
0
34
56
0
0
0
0
0
0
0
0
23
45
0
23
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _