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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT4
All Species:
8.48
Human Site:
Y277
Identified Species:
23.33
UniProt:
Q8N9L9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9L9
NP_689544.3
421
46327
Y277
S
S
I
P
P
L
G
Y
D
L
R
R
I
K
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091182
421
46346
Y277
S
S
I
P
P
L
G
Y
D
L
R
R
I
K
V
Dog
Lupus familis
XP_547893
420
46089
H276
T
F
I
P
P
L
G
H
D
L
R
R
I
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWN8
421
46462
H277
T
M
I
P
P
L
G
H
D
L
R
R
M
K
V
Rat
Rattus norvegicus
O88267
419
45995
I277
E
T
I
P
P
V
T
I
L
R
N
Q
V
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520064
421
46512
Y277
V
R
I
P
P
I
G
Y
N
L
R
R
I
R
I
Chicken
Gallus gallus
XP_426429
461
50969
W325
K
T
I
P
S
L
I
W
D
E
N
R
A
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690536
480
54118
L326
M
Y
I
P
P
L
T
L
D
F
K
K
K
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169107
421
46466
H277
T
M
I
P
P
L
G
H
D
L
R
R
T
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95
83.1
N.A.
74.3
66
N.A.
66.9
52.4
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.1
89.3
N.A.
85.9
78.3
N.A.
80.5
62.6
N.A.
57.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
80
N.A.
73.3
26.6
N.A.
60
40
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
60
N.A.
86.6
60
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
76.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
86.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% H
% Ile:
0
0
100
0
0
12
12
12
0
0
0
0
45
0
23
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
12
12
12
78
0
% K
% Leu:
0
0
0
0
0
78
0
12
12
67
0
0
0
0
0
% L
% Met:
12
23
0
0
0
0
0
0
0
0
0
0
12
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
23
0
0
0
0
% N
% Pro:
0
0
0
100
89
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
12
67
78
0
23
0
% R
% Ser:
23
23
0
0
12
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
34
23
0
0
0
0
23
0
0
0
0
0
12
0
0
% T
% Val:
12
0
0
0
0
12
0
0
0
0
0
0
12
0
67
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _