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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACOT4 All Species: 25.15
Human Site: Y214 Identified Species: 69.17
UniProt: Q8N9L9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N9L9 NP_689544.3 421 46327 Y214 Y F E E A V C Y M L Q H P Q V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091182 421 46346 Y214 Y F E E A L C Y M L Q H P Q V
Dog Lupus familis XP_547893 420 46089 Y213 Y F E E A L C Y M L Q H S E V
Cat Felis silvestris
Mouse Mus musculus Q8BWN8 421 46462 Y214 Y F E E A V R Y M L R H P K V
Rat Rattus norvegicus O88267 419 45995 Y214 Y F E E A V N Y L R G H P E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520064 421 46512 I214 Y F Q E A I N I M L R Q P Q V
Chicken Gallus gallus XP_426429 461 50969 Y262 Y F E E A V N Y M L Q H T Q V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690536 480 54118 F263 Y F E E G I D F L R Q Q P E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169107 421 46466 Y214 Y F E E A V C Y M L Q H P K V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95 83.1 N.A. 74.3 66 N.A. 66.9 52.4 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 97.1 89.3 N.A. 85.9 78.3 N.A. 80.5 62.6 N.A. 57.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 80 N.A. 80 66.6 N.A. 60 86.6 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 80 N.A. 80 86.6 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 76.9 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 86.2 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 93.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 100 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 89 100 0 0 0 0 0 0 0 0 0 34 0 % E
% Phe: 0 100 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 0 0 0 0 0 12 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 78 0 0 0 % H
% Ile: 0 0 0 0 0 23 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 % K
% Leu: 0 0 0 0 0 23 0 0 23 78 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 78 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 67 23 0 45 0 % Q
% Arg: 0 0 0 0 0 0 12 0 0 23 23 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % T
% Val: 0 0 0 0 0 56 0 0 0 0 0 0 0 0 100 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 100 0 0 0 0 0 0 78 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _