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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF454
All Species:
15.45
Human Site:
S397
Identified Species:
68
UniProt:
Q8N9F8
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9F8
NP_872400.1
522
60008
S397
G
K
A
F
R
D
N
S
S
F
A
R
H
R
K
Chimpanzee
Pan troglodytes
XP_527146
459
52579
K341
S
S
F
A
R
H
R
K
I
H
T
G
E
K
P
Rhesus Macaque
Macaca mulatta
XP_001102468
531
60858
S406
G
K
A
F
R
D
N
S
S
F
A
R
H
R
K
Dog
Lupus familis
XP_531878
1216
139765
S1091
G
K
A
F
R
D
N
S
S
F
A
R
H
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSH9
737
84009
S438
G
K
A
F
S
Y
W
S
S
L
A
Q
H
L
K
Rat
Rattus norvegicus
Q4V8A8
633
72419
T507
G
K
A
F
K
R
S
T
S
F
I
E
H
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
91.9
36.1
N.A.
40.1
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
94.1
40.2
N.A.
51.5
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
60
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
84
17
0
0
0
0
0
0
67
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
17
17
0
0
% E
% Phe:
0
0
17
84
0
0
0
0
0
67
0
0
0
0
0
% F
% Gly:
84
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
17
0
0
0
17
0
0
84
17
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
0
17
0
0
0
0
% I
% Lys:
0
84
0
0
17
0
0
17
0
0
0
0
0
17
67
% K
% Leu:
0
0
0
0
0
0
0
0
0
17
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% Q
% Arg:
0
0
0
0
67
17
17
0
0
0
0
50
0
50
17
% R
% Ser:
17
17
0
0
17
0
17
67
84
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
17
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _