KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133A
All Species:
11.82
Human Site:
T146
Identified Species:
28.89
UniProt:
Q8N9E0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N9E0
NP_775969.1
248
28941
T146
Y
K
S
S
Q
S
S
T
H
E
S
E
S
E
S
Chimpanzee
Pan troglodytes
XP_519200
223
25539
H140
K
K
K
K
N
R
S
H
K
S
S
E
S
S
M
Rhesus Macaque
Macaca mulatta
XP_001085869
248
28870
T146
Y
K
S
S
Q
S
S
T
Y
E
S
E
S
E
S
Dog
Lupus familis
XP_851208
250
29108
T145
Y
K
S
S
E
S
S
T
Y
E
S
G
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
G147
H
K
S
P
E
S
S
G
S
D
S
A
S
D
S
Rat
Rattus norvegicus
Q505I5
245
28015
V147
H
K
S
P
E
T
S
V
S
D
S
D
S
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
S166
G
G
S
L
R
G
P
S
S
D
V
G
S
V
H
Chicken
Gallus gallus
Q5ZLM8
250
28336
S149
S
R
K
S
S
S
S
S
A
S
E
S
E
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
D162
R
K
A
S
D
E
T
D
S
E
S
E
T
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
R97
K
K
K
K
K
R
E
R
S
P
S
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.7
92.3
90
N.A.
76.6
76.2
N.A.
48
73.1
N.A.
58.6
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
81.4
94.3
94.4
N.A.
85
85
N.A.
57.6
83.1
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
33.3
93.3
80
N.A.
46.6
40
N.A.
13.3
20
N.A.
40
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
33.3
100
93.3
N.A.
73.3
80
N.A.
33.3
33.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
30
0
10
0
30
10
% D
% Glu:
0
0
0
0
30
10
10
0
0
40
10
40
10
30
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
10
0
10
0
0
0
20
0
0
0
% G
% His:
20
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
80
30
20
10
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
20
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
20
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
60
50
10
50
70
20
50
20
80
20
80
30
70
% S
% Thr:
0
0
0
0
0
10
10
30
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
30
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _