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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX18 All Species: 24.55
Human Site: Y148 Identified Species: 45
UniProt: Q8N8Q8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N8Q8 NP_776188.1 333 37063 Y148 K R D A R L T Y L K N M R R L
Chimpanzee Pan troglodytes XP_517237 334 37115 Y148 K R D A R L T Y L K N M R R L
Rhesus Macaque Macaca mulatta XP_001104459 333 36848 Y148 E R V A R L T Y L K N M K R I
Dog Lupus familis XP_539312 333 36491 Y147 K R V A R L T Y L K N M R R L
Cat Felis silvestris
Mouse Mus musculus Q8VC74 331 36343 Y145 K R V A R L T Y L K N M R R L
Rat Rattus norvegicus NP_001099470 331 36300 Y145 K R V A R L T Y L K N I R R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511643 248 27826 L69 C H P F K A T L L V W I Q L P
Chicken Gallus gallus XP_420604 364 40246 F135 E K V A R F H F K K K L R R I
Frog Xenopus laevis NP_001090111 381 42844 F195 D K V A R F Q F R K N L R R I
Zebra Danio Brachydanio rerio NP_001107941 328 36390 F141 E Q T C R F H F K K N L R R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648286 351 39277 Y152 E K Q T Q I V Y R R S I K K Q
Honey Bee Apis mellifera XP_001120913 347 40227 F156 P Y R A H Y L F T R D F N K E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784727 340 38561 F130 E K R A Q R A F V G L V R R Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 93.9 79.2 N.A. 77.1 75.6 N.A. 49.2 52.7 50.1 52.2 N.A. 33.9 29.1 N.A. 42.3
Protein Similarity: 100 99.6 95.8 82.5 N.A. 84.9 83.4 N.A. 59.1 64.5 66.6 70.5 N.A. 54.1 51.5 N.A. 59.4
P-Site Identity: 100 100 73.3 93.3 N.A. 93.3 86.6 N.A. 13.3 33.3 40 33.3 N.A. 6.6 6.6 N.A. 20
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 33.3 66.6 66.6 66.6 N.A. 66.6 33.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 77 0 8 8 0 0 0 0 0 0 0 0 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 16 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 39 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 8 0 24 0 39 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 8 0 0 8 0 16 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 24 0 0 31 % I
% Lys: 39 31 0 0 8 0 0 0 16 70 8 0 16 16 0 % K
% Leu: 0 0 0 0 0 47 8 8 54 0 8 24 0 8 39 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 62 0 8 0 0 % N
% Pro: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 8 8 0 16 0 8 0 0 0 0 0 8 0 8 % Q
% Arg: 0 47 16 0 70 8 0 0 16 16 0 0 70 77 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % S
% Thr: 0 0 8 8 0 0 54 0 8 0 0 0 0 0 0 % T
% Val: 0 0 47 0 0 0 8 0 8 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 0 54 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _