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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX18
All Species:
35.45
Human Site:
S157
Identified Species:
65
UniProt:
Q8N8Q8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8Q8
NP_776188.1
333
37063
S157
K
N
M
R
R
L
I
S
E
L
Y
V
R
D
N
Chimpanzee
Pan troglodytes
XP_517237
334
37115
S157
K
N
M
R
R
L
I
S
E
L
Y
V
R
D
N
Rhesus Macaque
Macaca mulatta
XP_001104459
333
36848
S157
K
N
M
K
R
I
I
S
E
L
Y
V
R
D
N
Dog
Lupus familis
XP_539312
333
36491
S156
K
N
M
R
R
L
V
S
E
L
Y
V
R
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC74
331
36343
S154
K
N
M
R
R
L
V
S
E
L
Y
V
R
D
N
Rat
Rattus norvegicus
NP_001099470
331
36300
S154
K
N
I
R
R
L
V
S
E
L
Y
V
R
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511643
248
27826
W78
V
W
I
Q
L
P
M
W
V
V
V
S
V
A
L
Chicken
Gallus gallus
XP_420604
364
40246
T144
K
K
L
R
R
I
I
T
E
L
Y
I
R
D
N
Frog
Xenopus laevis
NP_001090111
381
42844
S204
K
N
L
R
R
I
T
S
G
L
Y
V
R
D
N
Zebra Danio
Brachydanio rerio
NP_001107941
328
36390
S150
K
N
L
R
R
I
V
S
E
L
Y
V
R
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648286
351
39277
Q161
R
S
I
K
K
Q
W
Q
N
L
I
V
R
D
N
Honey Bee
Apis mellifera
XP_001120913
347
40227
K165
R
D
F
N
K
E
Q
K
Q
L
Y
I
K
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784727
340
38561
K139
G
L
V
R
R
Y
S
K
E
L
Y
V
R
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
93.9
79.2
N.A.
77.1
75.6
N.A.
49.2
52.7
50.1
52.2
N.A.
33.9
29.1
N.A.
42.3
Protein Similarity:
100
99.6
95.8
82.5
N.A.
84.9
83.4
N.A.
59.1
64.5
66.6
70.5
N.A.
54.1
51.5
N.A.
59.4
P-Site Identity:
100
100
86.6
93.3
N.A.
93.3
86.6
N.A.
0
66.6
73.3
73.3
N.A.
33.3
20
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
93.3
86.6
100
N.A.
66.6
66.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
77
0
% D
% Glu:
0
0
0
0
0
8
0
0
70
0
0
0
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
24
0
0
31
31
0
0
0
8
16
0
0
0
% I
% Lys:
70
8
0
16
16
0
0
16
0
0
0
0
8
0
0
% K
% Leu:
0
8
24
0
8
39
0
0
0
93
0
0
0
0
8
% L
% Met:
0
0
39
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
62
0
8
0
0
0
0
8
0
0
0
0
8
93
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
8
8
8
0
0
0
0
0
0
% Q
% Arg:
16
0
0
70
77
0
0
0
0
0
0
0
85
0
0
% R
% Ser:
0
8
0
0
0
0
8
62
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
31
0
8
8
8
77
8
0
0
% V
% Trp:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
85
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _