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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 5.45
Human Site: S275 Identified Species: 20
UniProt: Q8N8Q3 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N8Q3 NP_001158109.1 282 30792 S275 V A C P K G D S G E S S A L C
Chimpanzee Pan troglodytes XP_001161219 310 33758 S276 V A C P K R D S G E S S G E G
Rhesus Macaque Macaca mulatta XP_001110357 390 42899
Dog Lupus familis XP_850549 442 47939 A275 K I R W E S L A R M V T A G G
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420082 285 31139 H275 A E L E G K S H S G R N G E D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794487 329 36819 D277 K H R K K D P D G A L G K T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567868 277 30863 S263 L Q K H Q T E S F K E L A V R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.1 60.5 50.9 N.A. N.A. N.A. N.A. N.A. 60 N.A. N.A. N.A. N.A. N.A. N.A. 45.2
Protein Similarity: 100 85.1 62.3 58.1 N.A. N.A. N.A. N.A. N.A. 73.3 N.A. N.A. N.A. N.A. N.A. N.A. 61.7
P-Site Identity: 100 73.3 0 6.6 N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 73.3 0 26.6 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 43.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 29 0 0 0 0 0 15 0 15 0 0 43 0 0 % A
% Cys: 0 0 29 0 0 0 0 0 0 0 0 0 0 0 15 % C
% Asp: 0 0 0 0 0 15 29 15 0 0 0 0 0 0 15 % D
% Glu: 0 15 0 15 15 0 15 0 0 29 15 0 0 29 15 % E
% Phe: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 15 15 0 0 43 15 0 15 29 15 29 % G
% His: 0 15 0 15 0 0 0 15 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 29 0 15 15 43 15 0 0 0 15 0 0 15 0 0 % K
% Leu: 15 0 15 0 0 0 15 0 0 0 15 15 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % N
% Pro: 0 0 0 29 0 0 15 0 0 0 0 0 0 0 0 % P
% Gln: 0 15 0 0 15 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 29 0 0 15 0 0 15 0 15 0 0 0 15 % R
% Ser: 0 0 0 0 0 15 15 43 15 0 29 29 0 0 0 % S
% Thr: 0 0 0 0 0 15 0 0 0 0 0 15 0 15 0 % T
% Val: 29 0 0 0 0 0 0 0 0 0 15 0 0 15 0 % V
% Trp: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _