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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX51
All Species:
31.82
Human Site:
Y646
Identified Species:
46.67
UniProt:
Q8N8A6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8A6
NP_778236.2
666
72457
Y646
L
Q
P
L
V
P
R
Y
E
E
A
L
S
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105887
664
72524
Y644
L
Q
P
L
V
P
R
Y
E
E
A
L
S
Q
L
Dog
Lupus familis
XP_543351
631
69099
Y611
L
Q
P
L
V
P
R
Y
E
E
A
L
S
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9R1
639
70349
Y619
L
Q
P
L
V
A
R
Y
E
T
A
L
S
Q
L
Rat
Rattus norvegicus
NP_001100620
601
66301
Y581
L
Q
P
L
V
A
R
Y
E
T
A
L
S
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512662
652
71903
P635
I
R
R
E
L
L
E
P
L
V
P
Q
Y
Q
A
Chicken
Gallus gallus
XP_415229
764
84078
Y744
L
K
P
L
V
Q
Q
Y
E
E
A
L
S
K
L
Frog
Xenopus laevis
NP_001121235
678
76560
Y658
L
K
Q
Y
E
Q
R
Y
E
E
A
L
S
E
L
Zebra Danio
Brachydanio rerio
Q6DRI7
652
72442
Y632
L
K
S
M
E
S
R
Y
E
Q
V
L
A
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26802
687
77572
Y589
E
I
Q
H
A
V
E
Y
K
E
A
L
A
G
L
Honey Bee
Apis mellifera
XP_001122539
439
49319
H422
K
Q
V
G
I
F
K
H
M
L
N
N
A
H
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797208
720
80444
S703
F
I
R
K
K
E
A
S
G
I
C
L
T
D
D
Poplar Tree
Populus trichocarpa
XP_002305441
518
57823
V501
E
T
S
R
K
G
K
V
G
I
K
F
S
R
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193320
522
57697
N505
G
R
Q
A
F
R
H
N
S
R
T
G
N
S
Q
Baker's Yeast
Sacchar. cerevisiae
P53734
629
70343
S609
F
T
L
L
E
S
D
S
E
L
Y
T
S
S
L
Red Bread Mold
Neurospora crassa
Q7RY59
515
56707
K498
H
G
G
L
L
K
R
K
R
G
N
G
Q
G
G
Conservation
Percent
Protein Identity:
100
N.A.
93.9
75.5
N.A.
76.4
71.1
N.A.
59
52
51.1
48.5
N.A.
36
30.4
N.A.
38.4
Protein Similarity:
100
N.A.
97.1
82.7
N.A.
83.9
78
N.A.
70.1
64.7
68.2
65.4
N.A.
51.3
44.2
N.A.
55.4
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
6.6
73.3
60
40
N.A.
33.3
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
26.6
93.3
73.3
73.3
N.A.
46.6
33.3
N.A.
13.3
Percent
Protein Identity:
26.1
N.A.
N.A.
26.7
24.6
21
Protein Similarity:
41.7
N.A.
N.A.
40.6
43.2
36.3
P-Site Identity:
6.6
N.A.
N.A.
0
26.6
13.3
P-Site Similarity:
26.6
N.A.
N.A.
13.3
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
13
7
0
0
0
50
0
19
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
7
% D
% Glu:
13
0
0
7
19
7
13
0
57
38
0
0
0
13
0
% E
% Phe:
13
0
0
0
7
7
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
7
7
7
0
7
0
0
13
7
0
13
0
13
7
% G
% His:
7
0
0
7
0
0
7
7
0
0
0
0
0
7
0
% H
% Ile:
7
13
0
0
7
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
7
19
0
7
13
7
13
7
7
0
7
0
0
7
7
% K
% Leu:
50
0
7
50
13
7
0
0
7
13
0
63
0
0
63
% L
% Met:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
13
7
7
0
0
% N
% Pro:
0
0
38
0
0
19
0
7
0
0
7
0
0
0
0
% P
% Gln:
0
38
19
0
0
13
7
0
0
7
0
7
7
38
7
% Q
% Arg:
0
13
13
7
0
7
50
0
7
7
0
0
0
7
0
% R
% Ser:
0
0
13
0
0
13
0
13
7
0
0
0
57
13
0
% S
% Thr:
0
13
0
0
0
0
0
0
0
13
7
7
7
0
0
% T
% Val:
0
0
7
0
38
7
0
7
0
7
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
57
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _