KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX51
All Species:
32.73
Human Site:
Y580
Identified Species:
48
UniProt:
Q8N8A6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8A6
NP_778236.2
666
72457
Y580
G
V
E
L
V
V
N
Y
D
A
P
Q
Y
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105887
664
72524
Y578
G
V
E
L
V
V
N
Y
D
A
P
Q
Y
L
R
Dog
Lupus familis
XP_543351
631
69099
Y545
G
V
Q
L
V
I
N
Y
D
A
P
Q
Y
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9R1
639
70349
Y553
G
V
E
L
V
I
N
Y
D
A
P
Q
Y
L
R
Rat
Rattus norvegicus
NP_001100620
601
66301
K515
Y
G
P
G
Q
R
K
K
I
L
K
Q
F
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512662
652
71903
K569
G
I
D
V
E
G
V
K
L
V
I
N
Y
D
A
Chicken
Gallus gallus
XP_415229
764
84078
Y678
G
V
N
C
V
I
N
Y
D
T
P
Q
F
I
R
Frog
Xenopus laevis
NP_001121235
678
76560
Y592
G
V
K
C
I
I
N
Y
D
A
P
Q
F
I
R
Zebra Danio
Brachydanio rerio
Q6DRI7
652
72442
Y566
G
V
K
C
V
I
N
Y
D
A
P
Q
Y
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26802
687
77572
Y523
D
V
D
V
V
L
S
Y
E
T
P
R
H
I
T
Honey Bee
Apis mellifera
XP_001122539
439
49319
N356
K
I
L
N
K
F
I
N
G
K
I
Q
I
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797208
720
80444
K637
S
E
R
Q
N
I
L
K
Q
F
K
A
G
K
I
Poplar Tree
Populus trichocarpa
XP_002305441
518
57823
Q435
G
R
T
A
R
A
G
Q
T
G
R
C
I
T
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193320
522
57697
F439
A
G
Q
A
G
R
C
F
T
L
L
S
N
H
E
Baker's Yeast
Sacchar. cerevisiae
P53734
629
70343
Y543
D
I
T
Q
V
I
N
Y
D
P
P
M
S
S
Q
Red Bread Mold
Neurospora crassa
Q7RY59
515
56707
S432
G
K
S
G
H
A
I
S
I
V
T
Q
Y
D
L
Conservation
Percent
Protein Identity:
100
N.A.
93.9
75.5
N.A.
76.4
71.1
N.A.
59
52
51.1
48.5
N.A.
36
30.4
N.A.
38.4
Protein Similarity:
100
N.A.
97.1
82.7
N.A.
83.9
78
N.A.
70.1
64.7
68.2
65.4
N.A.
51.3
44.2
N.A.
55.4
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
6.6
N.A.
13.3
60
60
73.3
N.A.
26.6
13.3
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
33.3
80
93.3
93.3
N.A.
80
20
N.A.
6.6
Percent
Protein Identity:
26.1
N.A.
N.A.
26.7
24.6
21
Protein Similarity:
41.7
N.A.
N.A.
40.6
43.2
36.3
P-Site Identity:
6.6
N.A.
N.A.
0
33.3
20
P-Site Similarity:
6.6
N.A.
N.A.
13.3
53.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
13
0
13
0
0
0
38
0
7
0
0
7
% A
% Cys:
0
0
0
19
0
0
7
0
0
0
0
7
0
0
0
% C
% Asp:
13
0
13
0
0
0
0
0
50
0
0
0
0
13
0
% D
% Glu:
0
7
19
0
7
0
0
0
7
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
7
0
7
0
7
0
0
19
0
0
% F
% Gly:
63
13
0
13
7
7
7
0
7
7
0
0
7
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
19
0
0
7
44
13
0
13
0
13
0
13
25
13
% I
% Lys:
7
7
13
0
7
0
7
19
0
7
13
0
0
7
0
% K
% Leu:
0
0
7
25
0
7
7
0
7
13
7
0
0
32
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
7
7
0
50
7
0
0
0
7
7
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
7
57
0
0
0
0
% P
% Gln:
0
0
13
13
7
0
0
7
7
0
0
63
0
0
13
% Q
% Arg:
0
7
7
0
7
13
0
0
0
0
7
7
0
0
44
% R
% Ser:
7
0
7
0
0
0
7
7
0
0
0
7
7
7
0
% S
% Thr:
0
0
13
0
0
0
0
0
13
13
7
0
0
7
7
% T
% Val:
0
50
0
13
50
13
7
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
57
0
0
0
0
44
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _