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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX51 All Species: 19.39
Human Site: T622 Identified Species: 28.44
UniProt: Q8N8A6 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N8A6 NP_778236.2 666 72457 T622 R R F L R M L T E A G A P E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105887 664 72524 T620 R R F L Q M L T E A G A P E L
Dog Lupus familis XP_543351 631 69099 A587 R R F L Q M L A E A G V P K M
Cat Felis silvestris
Mouse Mus musculus Q6P9R1 639 70349 S595 R K F L Q M V S E A G V P E L
Rat Rattus norvegicus NP_001100620 601 66301 S557 R K F L Q M V S E A G V P E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512662 652 71903 F611 L K V Q E Q K F L R M L R E A
Chicken Gallus gallus XP_415229 764 84078 K720 R R F L R M L K D A G I P D I
Frog Xenopus laevis NP_001121235 678 76560 R634 K P Y F G M L R D A G A P E L
Zebra Danio Brachydanio rerio Q6DRI7 652 72442 S608 K R F L K M V S D A G S P G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26802 687 77572 S565 T L F K K I L S D A N K G L G
Honey Bee Apis mellifera XP_001122539 439 49319 R398 G Y I H R A G R T G R A G K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797208 720 80444 H679 P H L K T Y I H R V G R T A R
Poplar Tree Populus trichocarpa XP_002305441 518 57823 H477 S S S V K S L H P F Y L S A L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193320 522 57697 P481 S I R A T Y T P A L E K L K E
Baker's Yeast Sacchar. cerevisiae P53734 629 70343 N585 R T F F D D L N K D L D R D G
Red Bread Mold Neurospora crassa Q7RY59 515 56707 Q474 K P R V E E A Q R H A R N E M
Conservation
Percent
Protein Identity: 100 N.A. 93.9 75.5 N.A. 76.4 71.1 N.A. 59 52 51.1 48.5 N.A. 36 30.4 N.A. 38.4
Protein Similarity: 100 N.A. 97.1 82.7 N.A. 83.9 78 N.A. 70.1 64.7 68.2 65.4 N.A. 51.3 44.2 N.A. 55.4
P-Site Identity: 100 N.A. 93.3 66.6 N.A. 66.6 66.6 N.A. 6.6 66.6 53.3 46.6 N.A. 20 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. 13.3 86.6 73.3 93.3 N.A. 46.6 20 N.A. 13.3
Percent
Protein Identity: 26.1 N.A. N.A. 26.7 24.6 21
Protein Similarity: 41.7 N.A. N.A. 40.6 43.2 36.3
P-Site Identity: 13.3 N.A. N.A. 0 20 6.6
P-Site Similarity: 26.6 N.A. N.A. 6.6 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 7 7 7 57 7 25 0 13 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 7 0 0 25 7 0 7 0 13 0 % D
% Glu: 0 0 0 0 13 7 0 0 32 0 7 0 0 44 7 % E
% Phe: 0 0 57 13 0 0 0 7 0 7 0 0 0 0 0 % F
% Gly: 7 0 0 0 7 0 7 0 0 7 57 0 13 7 13 % G
% His: 0 7 0 7 0 0 0 13 0 7 0 0 0 0 0 % H
% Ile: 0 7 7 0 0 7 7 0 0 0 0 7 0 0 13 % I
% Lys: 19 19 0 13 19 0 7 7 7 0 0 13 0 19 0 % K
% Leu: 7 7 7 44 0 0 50 0 7 7 7 13 7 7 38 % L
% Met: 0 0 0 0 0 50 0 0 0 0 7 0 0 0 13 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 7 0 7 0 0 % N
% Pro: 7 13 0 0 0 0 0 7 7 0 0 0 50 0 0 % P
% Gln: 0 0 0 7 25 7 0 7 0 0 0 0 0 0 0 % Q
% Arg: 44 32 13 0 19 0 0 13 13 7 7 13 13 0 7 % R
% Ser: 13 7 7 0 0 7 0 25 0 0 0 7 7 0 7 % S
% Thr: 7 7 0 0 13 0 7 13 7 0 0 0 7 0 0 % T
% Val: 0 0 7 13 0 0 19 0 0 7 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 0 13 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _