Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX51 All Species: 39.39
Human Site: S255 Identified Species: 57.78
UniProt: Q8N8A6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N8A6 NP_778236.2 666 72457 S255 R P S D L C V S A P T G S G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105887 664 72524 S253 R P S D L C V S A P T G S G K
Dog Lupus familis XP_543351 631 69099 S219 R P S D L C V S A P T G S G K
Cat Felis silvestris
Mouse Mus musculus Q6P9R1 639 70349 S227 Q P S D L C V S A P T G S G K
Rat Rattus norvegicus NP_001100620 601 66301 D205 P A L L E S A D N G F L V G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512662 652 71903 S255 R P R D I C V S A P T G S G K
Chicken Gallus gallus XP_415229 764 84078 S350 R P K D I C V S A P T G S G K
Frog Xenopus laevis NP_001121235 678 76560 S265 R P S D V C V S A P T G S G K
Zebra Danio Brachydanio rerio Q6DRI7 652 72442 S246 R P R D V C V S A P T G S G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26802 687 77572 S189 R P R D I C V S A P T G S G K
Honey Bee Apis mellifera XP_001122539 439 49319 H52 G P S L E E L H S I L D L K L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797208 720 80444 S320 R P R D L C I S A P T G S G K
Poplar Tree Populus trichocarpa XP_002305441 518 57823 A131 V F A A I A P A M G L S V G L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193320 522 57697 V135 A P A V G L S V G S A V G Q S
Baker's Yeast Sacchar. cerevisiae P53734 629 70343 N233 R I G D I L V N A A T G S G K
Red Bread Mold Neurospora crassa Q7RY59 515 56707 R128 I P L A L Q N R D I I G I A E
Conservation
Percent
Protein Identity: 100 N.A. 93.9 75.5 N.A. 76.4 71.1 N.A. 59 52 51.1 48.5 N.A. 36 30.4 N.A. 38.4
Protein Similarity: 100 N.A. 97.1 82.7 N.A. 83.9 78 N.A. 70.1 64.7 68.2 65.4 N.A. 51.3 44.2 N.A. 55.4
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 6.6 N.A. 86.6 86.6 93.3 86.6 N.A. 86.6 13.3 N.A. 86.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 13.3 N.A. 93.3 93.3 100 93.3 N.A. 93.3 26.6 N.A. 93.3
Percent
Protein Identity: 26.1 N.A. N.A. 26.7 24.6 21
Protein Similarity: 41.7 N.A. N.A. 40.6 43.2 36.3
P-Site Identity: 6.6 N.A. N.A. 6.6 60 20
P-Site Similarity: 26.6 N.A. N.A. 13.3 73.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 13 13 0 7 7 7 69 7 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 63 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 69 0 0 0 7 7 0 0 7 0 0 0 % D
% Glu: 0 0 0 0 13 7 0 0 0 0 0 0 0 0 7 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 7 0 7 0 7 0 0 0 7 13 0 75 7 82 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 32 0 7 0 0 13 7 0 7 0 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 69 % K
% Leu: 0 0 13 13 38 13 7 0 0 0 13 7 7 0 13 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 7 7 0 0 0 0 0 0 % N
% Pro: 7 82 0 0 0 0 7 0 0 63 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % Q
% Arg: 63 0 25 0 0 0 0 7 0 0 0 0 0 0 7 % R
% Ser: 0 0 38 0 0 7 7 63 7 7 0 7 69 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 69 0 0 0 0 % T
% Val: 7 0 0 7 13 0 63 7 0 0 0 7 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _