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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX51
All Species:
19.09
Human Site:
S250
Identified Species:
28
UniProt:
Q8N8A6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N8A6
NP_778236.2
666
72457
S250
G
R
G
G
Y
R
P
S
D
L
C
V
S
A
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105887
664
72524
S248
G
R
G
G
Y
R
P
S
D
L
C
V
S
A
P
Dog
Lupus familis
XP_543351
631
69099
S214
A
R
G
G
Y
R
P
S
D
L
C
V
S
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9R1
639
70349
S222
G
R
G
G
Y
Q
P
S
D
L
C
V
S
A
P
Rat
Rattus norvegicus
NP_001100620
601
66301
L200
Q
A
A
V
I
P
A
L
L
E
S
A
D
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512662
652
71903
R250
G
R
G
G
Y
R
P
R
D
I
C
V
S
A
P
Chicken
Gallus gallus
XP_415229
764
84078
K345
G
Q
G
G
Y
R
P
K
D
I
C
V
S
A
P
Frog
Xenopus laevis
NP_001121235
678
76560
S260
G
K
G
G
Y
R
P
S
D
V
C
V
S
A
P
Zebra Danio
Brachydanio rerio
Q6DRI7
652
72442
R241
G
P
G
G
Y
R
P
R
D
V
C
V
S
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26802
687
77572
R184
K
P
P
P
F
R
P
R
D
I
C
V
S
A
P
Honey Bee
Apis mellifera
XP_001122539
439
49319
S47
V
D
L
D
S
G
P
S
L
E
E
L
H
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797208
720
80444
R315
G
H
A
G
Y
R
P
R
D
L
C
I
S
A
P
Poplar Tree
Populus trichocarpa
XP_002305441
518
57823
A126
L
Q
V
K
Q
V
F
A
A
I
A
P
A
M
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193320
522
57697
A130
V
F
D
A
I
A
P
A
V
G
L
S
V
G
S
Baker's Yeast
Sacchar. cerevisiae
P53734
629
70343
G228
R
N
F
T
R
R
I
G
D
I
L
V
N
A
A
Red Bread Mold
Neurospora crassa
Q7RY59
515
56707
L123
I
Q
E
Q
S
I
P
L
A
L
Q
N
R
D
I
Conservation
Percent
Protein Identity:
100
N.A.
93.9
75.5
N.A.
76.4
71.1
N.A.
59
52
51.1
48.5
N.A.
36
30.4
N.A.
38.4
Protein Similarity:
100
N.A.
97.1
82.7
N.A.
83.9
78
N.A.
70.1
64.7
68.2
65.4
N.A.
51.3
44.2
N.A.
55.4
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
0
N.A.
86.6
80
86.6
80
N.A.
53.3
13.3
N.A.
73.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
0
N.A.
93.3
93.3
100
86.6
N.A.
66.6
26.6
N.A.
80
Percent
Protein Identity:
26.1
N.A.
N.A.
26.7
24.6
21
Protein Similarity:
41.7
N.A.
N.A.
40.6
43.2
36.3
P-Site Identity:
0
N.A.
N.A.
6.6
26.6
13.3
P-Site Similarity:
26.6
N.A.
N.A.
13.3
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
13
7
0
7
7
13
13
0
7
7
7
69
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
0
% C
% Asp:
0
7
7
7
0
0
0
0
69
0
0
0
7
7
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
13
7
0
0
0
0
% E
% Phe:
0
7
7
0
7
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
50
57
0
7
0
7
0
7
0
0
0
7
13
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
0
0
0
13
7
7
0
0
32
0
7
0
0
13
% I
% Lys:
7
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
7
0
7
0
0
0
0
13
13
38
13
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
7
7
7
0
% N
% Pro:
0
13
7
7
0
7
82
0
0
0
0
7
0
0
63
% P
% Gln:
7
19
0
7
7
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
7
32
0
0
7
63
0
25
0
0
0
0
7
0
0
% R
% Ser:
0
0
0
0
13
0
0
38
0
0
7
7
63
7
7
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
13
0
7
7
0
7
0
0
7
13
0
63
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
57
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _