KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHB
All Species:
14.85
Human Site:
Y435
Identified Species:
46.67
UniProt:
Q8N7U6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7U6
NP_653316.3
831
93557
Y435
G
E
A
K
N
R
K
Y
N
P
S
S
F
H
R
Chimpanzee
Pan troglodytes
XP_516318
669
76388
A320
A
K
F
V
S
K
R
A
D
D
F
K
E
K
F
Rhesus Macaque
Macaca mulatta
XP_001088383
669
76125
A320
A
K
F
V
S
K
R
A
D
D
F
K
E
K
F
Dog
Lupus familis
XP_542768
881
99192
Y485
G
E
A
K
N
R
K
Y
N
P
S
S
F
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU5
853
95666
Y457
G
E
A
K
N
R
K
Y
N
P
A
S
F
H
R
Rat
Rattus norvegicus
NP_001100349
852
95791
Y456
G
E
A
K
N
R
K
Y
N
P
A
S
F
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425999
612
68605
T263
Q
M
K
R
A
A
K
T
V
S
K
R
I
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783931
592
66072
T243
N
G
K
N
V
A
Q
T
L
K
W
L
R
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
76.5
74.6
N.A.
66.5
66.6
N.A.
N.A.
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
79.9
78.6
82.1
N.A.
76.6
77.1
N.A.
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.7
P-Site Identity:
100
0
0
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
50
0
13
25
0
25
0
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
25
25
0
0
0
13
25
% D
% Glu:
0
50
0
0
0
0
0
0
0
0
0
0
25
0
0
% E
% Phe:
0
0
25
0
0
0
0
0
0
0
25
0
50
0
25
% F
% Gly:
50
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% I
% Lys:
0
25
25
50
0
25
63
0
0
13
13
25
0
25
0
% K
% Leu:
0
0
0
0
0
0
0
0
13
0
0
13
0
0
0
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
13
50
0
0
0
50
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
50
25
0
0
0
0
13
13
0
50
% R
% Ser:
0
0
0
0
25
0
0
0
0
13
25
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
25
13
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _