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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHB
All Species:
13.94
Human Site:
Y425
Identified Species:
43.81
UniProt:
Q8N7U6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7U6
NP_653316.3
831
93557
Y425
Y
V
V
S
H
N
D
Y
Y
A
G
E
A
K
N
Chimpanzee
Pan troglodytes
XP_516318
669
76388
K310
W
L
H
E
L
Q
M
K
R
G
A
K
F
V
S
Rhesus Macaque
Macaca mulatta
XP_001088383
669
76125
K310
W
L
H
E
L
Q
M
K
R
G
A
K
F
V
S
Dog
Lupus familis
XP_542768
881
99192
Y475
Y
I
V
S
H
N
D
Y
Y
A
G
E
A
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU5
853
95666
Y447
Y
T
V
S
H
N
D
Y
F
A
G
E
A
K
N
Rat
Rattus norvegicus
NP_001100349
852
95791
Y446
Y
T
I
S
H
N
D
Y
F
A
G
E
A
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425999
612
68605
Y253
S
K
S
L
N
W
L
Y
D
W
Q
M
K
R
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783931
592
66072
H233
L
F
G
I
P
T
P
H
E
N
N
G
K
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
76.5
74.6
N.A.
66.5
66.6
N.A.
N.A.
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
79.9
78.6
82.1
N.A.
76.6
77.1
N.A.
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.7
P-Site Identity:
100
0
0
93.3
N.A.
86.6
80
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
26.6
100
N.A.
93.3
93.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
25
0
50
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
13
0
0
0
0
0
0
% D
% Glu:
0
0
0
25
0
0
0
0
13
0
0
50
0
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
25
0
0
0
25
0
0
% F
% Gly:
0
0
13
0
0
0
0
0
0
25
50
13
0
0
0
% G
% His:
0
0
25
0
50
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
13
13
13
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
0
0
0
0
0
25
0
0
0
25
25
50
0
% K
% Leu:
13
25
0
13
25
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
25
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
13
50
0
0
0
13
13
0
0
13
50
% N
% Pro:
0
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
25
0
0
0
0
13
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
25
0
0
0
0
13
0
% R
% Ser:
13
0
13
50
0
0
0
0
0
0
0
0
0
0
25
% S
% Thr:
0
25
0
0
0
13
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
38
0
0
0
0
0
0
0
0
0
0
25
13
% V
% Trp:
25
0
0
0
0
13
0
0
0
13
0
0
0
0
0
% W
% Tyr:
50
0
0
0
0
0
0
63
25
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _