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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAF1
All Species:
32.73
Human Site:
Y289
Identified Species:
65.45
UniProt:
Q8N7H5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7H5
NP_061961.2
531
59976
Y289
A
P
D
D
V
Y
D
Y
K
I
A
R
E
Y
N
Chimpanzee
Pan troglodytes
XP_001135849
203
23622
Rhesus Macaque
Macaca mulatta
XP_001086329
333
38828
K119
I
Q
A
P
T
S
S
K
R
S
Q
Q
H
A
K
Dog
Lupus familis
XP_533675
528
59752
Y289
A
P
D
D
V
Y
D
Y
K
I
A
R
E
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2T8
535
60500
Y289
A
P
D
D
V
Y
D
Y
K
I
A
R
E
Y
N
Rat
Rattus norvegicus
Q4V886
535
60528
Y289
A
P
D
D
V
Y
D
Y
K
I
A
R
E
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
A2BD83
524
59587
Y289
M
P
E
D
I
Y
D
Y
K
I
A
R
E
Y
N
Zebra Danio
Brachydanio rerio
Q4U0S5
503
58198
Y289
M
P
E
E
V
Y
E
Y
K
I
A
R
E
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649493
538
60776
Y289
K
E
E
E
E
Y
E
Y
K
I
A
R
E
Y
N
Honey Bee
Apis mellifera
XP_624998
548
62655
Y289
A
D
D
E
E
Y
E
Y
K
M
A
R
E
Y
N
Nematode Worm
Caenorhab. elegans
P90783
425
49879
A211
D
H
W
K
H
L
F
A
H
V
Q
F
D
G
D
Sea Urchin
Strong. purpuratus
XP_785518
539
62637
Y273
V
E
G
E
E
Y
E
Y
K
L
T
R
E
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37
62.5
98.6
N.A.
98.1
97.7
N.A.
N.A.
N.A.
80.2
74.3
N.A.
49.4
51.8
31
55.8
Protein Similarity:
100
37.4
62.7
99.2
N.A.
98.5
98.1
N.A.
N.A.
N.A.
85.6
83.4
N.A.
63.2
66.4
49.7
70.1
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
N.A.
N.A.
80
73.3
N.A.
60
66.6
0
46.6
P-Site Similarity:
100
0
13.3
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
80
86.6
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
9
0
0
0
0
9
0
0
67
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
42
42
0
0
42
0
0
0
0
0
9
0
9
% D
% Glu:
0
17
25
34
25
0
34
0
0
0
0
0
75
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
9
0
0
9
0
0
0
9
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
59
0
0
0
0
0
% I
% Lys:
9
0
0
9
0
0
0
9
75
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% L
% Met:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% N
% Pro:
0
50
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
17
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
75
0
0
0
% R
% Ser:
0
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% T
% Val:
9
0
0
0
42
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
75
0
75
0
0
0
0
0
75
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _