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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAF1
All Species:
10.91
Human Site:
S466
Identified Species:
21.82
UniProt:
Q8N7H5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7H5
NP_061961.2
531
59976
S466
D
S
E
D
D
A
D
S
D
D
E
D
R
G
Q
Chimpanzee
Pan troglodytes
XP_001135849
203
23622
E139
K
R
K
R
D
Q
E
E
E
M
D
Y
A
P
D
Rhesus Macaque
Macaca mulatta
XP_001086329
333
38828
K269
L
P
V
E
E
T
L
K
K
R
K
R
D
Q
E
Dog
Lupus familis
XP_533675
528
59752
D463
S
D
A
D
S
E
D
D
A
D
S
D
D
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2T8
535
60500
S466
D
S
E
D
D
A
D
S
D
D
E
D
R
G
Q
Rat
Rattus norvegicus
Q4V886
535
60528
S466
D
S
E
D
D
A
D
S
D
D
E
D
R
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
A2BD83
524
59587
D460
D
D
D
D
D
D
S
D
E
D
G
H
N
E
S
Zebra Danio
Brachydanio rerio
Q4U0S5
503
58198
K439
V
K
R
R
R
E
R
K
S
S
G
S
E
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649493
538
60776
A467
R
S
R
T
N
S
P
A
G
S
Q
K
S
G
S
Honey Bee
Apis mellifera
XP_624998
548
62655
S459
R
S
E
S
R
S
P
S
R
S
H
S
K
S
R
Nematode Worm
Caenorhab. elegans
P90783
425
49879
Q361
R
E
A
E
L
Y
E
Q
P
K
T
R
K
Q
E
Sea Urchin
Strong. purpuratus
XP_785518
539
62637
A432
G
E
E
E
E
Q
E
A
E
E
E
G
E
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37
62.5
98.6
N.A.
98.1
97.7
N.A.
N.A.
N.A.
80.2
74.3
N.A.
49.4
51.8
31
55.8
Protein Similarity:
100
37.4
62.7
99.2
N.A.
98.5
98.1
N.A.
N.A.
N.A.
85.6
83.4
N.A.
63.2
66.4
49.7
70.1
P-Site Identity:
100
6.6
0
26.6
N.A.
100
100
N.A.
N.A.
N.A.
26.6
0
N.A.
13.3
20
0
13.3
P-Site Similarity:
100
33.3
26.6
26.6
N.A.
100
100
N.A.
N.A.
N.A.
40
0
N.A.
40
40
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
25
0
17
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
17
9
42
42
9
34
17
25
42
9
34
17
0
17
% D
% Glu:
0
17
42
25
17
17
25
9
25
9
34
0
17
25
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
9
0
17
9
0
34
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
9
0
0
0
0
17
9
9
9
9
17
0
0
% K
% Leu:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
9
0
0
0
0
17
0
9
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
17
0
9
0
0
9
0
0
17
25
% Q
% Arg:
25
9
17
17
17
0
9
0
9
9
0
17
25
0
9
% R
% Ser:
9
42
0
9
9
17
9
34
9
25
9
17
9
17
17
% S
% Thr:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% T
% Val:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _