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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU5F2
All Species:
9.39
Human Site:
S273
Identified Species:
20.67
UniProt:
Q8N7G0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N7G0
NP_694948.1
328
36051
S273
S
R
P
T
N
D
A
S
P
R
E
I
V
G
T
Chimpanzee
Pan troglodytes
Q7YR49
360
38582
A293
K
R
S
S
S
D
Y
A
Q
R
E
D
F
E
A
Rhesus Macaque
Macaca mulatta
Q5TM49
360
38511
A293
K
R
S
S
S
D
Y
A
Q
R
E
D
F
E
A
Dog
Lupus familis
XP_538830
360
38329
S293
K
R
S
S
S
D
Y
S
Q
R
E
D
F
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAC9
329
36392
S262
S
W
P
T
N
D
T
S
R
R
E
D
V
G
A
Rat
Rattus norvegicus
P56225
335
36982
S268
G
W
P
T
N
D
S
S
Q
R
E
N
V
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001103648
295
33223
G233
K
R
L
L
L
P
F
G
N
E
S
E
G
V
M
Frog
Xenopus laevis
B7ZQA9
445
49017
I375
K
R
Q
V
Y
P
Y
I
R
E
N
G
G
E
P
Zebra Danio
Brachydanio rerio
Q90270
472
51486
D406
K
R
L
A
L
P
F
D
D
E
C
V
E
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16241
427
45909
T367
K
R
M
T
P
P
N
T
L
G
G
D
M
M
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20268
380
42556
N331
V
V
R
V
W
F
C
N
R
R
Q
K
E
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
48
47.7
N.A.
65.9
65.3
N.A.
N.A.
35
28.9
29
N.A.
28.5
N.A.
30
N.A.
Protein Similarity:
100
58.8
58.6
59.1
N.A.
76.9
76.7
N.A.
N.A.
48.4
40.2
41.3
N.A.
41.9
N.A.
43.4
N.A.
P-Site Identity:
100
26.6
26.6
33.3
N.A.
66.6
60
N.A.
N.A.
6.6
6.6
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
46.6
46.6
46.6
N.A.
66.6
66.6
N.A.
N.A.
6.6
6.6
13.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
19
0
0
0
0
0
10
46
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
55
0
10
10
0
0
46
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
28
55
10
19
37
0
% E
% Phe:
0
0
0
0
0
10
19
0
0
0
0
0
28
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
10
10
10
19
28
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
64
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
19
10
19
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
10
% M
% Asn:
0
0
0
0
28
0
10
10
10
0
10
10
0
0
0
% N
% Pro:
0
0
28
0
10
37
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
37
0
10
0
0
0
10
% Q
% Arg:
0
73
10
0
0
0
0
0
28
64
0
0
0
0
10
% R
% Ser:
19
0
28
28
28
0
10
37
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
37
0
0
10
10
0
0
0
0
0
0
10
% T
% Val:
10
10
0
19
0
0
0
0
0
0
0
10
28
10
0
% V
% Trp:
0
19
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
37
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _