KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1L
All Species:
34.55
Human Site:
Y276
Identified Species:
54.29
UniProt:
Q8N752
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N752
NP_660204.1
337
39086
Y276
E
E
V
P
D
Y
M
Y
L
R
Q
L
F
R
I
Chimpanzee
Pan troglodytes
XP_522662
337
39019
Y276
E
E
V
P
D
Y
M
Y
L
R
Q
L
F
R
I
Rhesus Macaque
Macaca mulatta
XP_001085343
337
38964
Y276
E
E
V
P
D
Y
M
Y
L
R
Q
L
F
R
I
Dog
Lupus familis
XP_867638
336
38749
Y276
E
E
A
P
D
Y
M
Y
L
R
Q
L
F
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
R355
V
A
S
T
P
A
S
R
I
Q
Q
T
G
N
T
Rat
Rattus norvegicus
P97633
325
37477
R267
L
N
Y
C
R
G
L
R
F
E
E
A
P
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
Y276
E
E
A
P
D
Y
M
Y
L
R
Q
L
F
R
I
Frog
Xenopus laevis
Q5BP74
415
47421
S350
S
T
P
L
T
P
T
S
H
T
A
N
T
S
P
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
R306
R
E
D
P
E
R
D
R
R
D
R
E
E
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
Y279
E
E
Q
P
D
Y
M
Y
L
R
Q
L
F
R
I
Honey Bee
Apis mellifera
XP_393612
350
40282
Y280
E
E
S
P
D
Y
M
Y
L
R
Q
L
F
R
I
Nematode Worm
Caenorhab. elegans
P42168
341
39018
Y275
D
E
S
P
D
Y
M
Y
L
R
Q
L
F
R
I
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
Y290
D
E
N
P
D
Y
V
Y
L
R
Q
L
F
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
H337
G
E
E
E
G
R
P
H
M
E
S
S
R
R
R
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
P427
G
Q
R
P
N
Y
Y
P
E
P
L
L
Q
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
90.5
N.A.
54.5
88.1
N.A.
N.A.
90.5
53.9
56.5
N.A.
70.6
76.2
75.3
74.1
Protein Similarity:
100
99.6
99.4
94.3
N.A.
66.1
91
N.A.
N.A.
94.6
66
68.2
N.A.
81.3
84
82.1
84.2
P-Site Identity:
100
100
100
93.3
N.A.
6.6
0
N.A.
N.A.
93.3
0
26.6
N.A.
93.3
93.3
86.6
80
P-Site Similarity:
100
100
100
93.3
N.A.
20
13.3
N.A.
N.A.
93.3
0
40
N.A.
93.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.7
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
0
0
7
0
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
7
0
60
0
7
0
0
7
0
0
0
7
0
% D
% Glu:
47
74
7
7
7
0
0
0
7
14
7
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
60
0
0
% F
% Gly:
14
0
0
0
7
7
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
67
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
7
0
0
7
0
60
0
7
67
0
0
0
% L
% Met:
0
0
0
0
0
0
54
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
7
0
0
0
0
0
0
7
0
7
0
% N
% Pro:
0
0
7
74
7
7
7
7
0
7
0
0
7
0
7
% P
% Gln:
0
7
7
0
0
0
0
0
0
7
67
0
7
7
7
% Q
% Arg:
7
0
7
0
7
14
0
20
7
60
7
0
7
74
7
% R
% Ser:
7
0
20
0
0
0
7
7
0
0
7
7
0
7
0
% S
% Thr:
0
7
0
7
7
0
7
0
0
7
0
7
7
0
7
% T
% Val:
7
0
20
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
67
7
60
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _