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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1A1L All Species: 38.79
Human Site: Y213 Identified Species: 60.95
UniProt: Q8N752 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N752 NP_660204.1 337 39086 Y213 S L G Y V F M Y F N R T S L P
Chimpanzee Pan troglodytes XP_522662 337 39019 Y213 S L G Y V F M Y F N R T S L P
Rhesus Macaque Macaca mulatta XP_001085343 337 38964 Y213 S L G Y V F M Y F N R T S L P
Dog Lupus familis XP_867638 336 38749 Y213 S L G Y V L M Y F N R T S L P
Cat Felis silvestris
Mouse Mus musculus Q9JMK2 416 47304 Y286 R Q G F S Y D Y V F D W N M L
Rat Rattus norvegicus P97633 325 37477 E205 Q S R R D D M E S L G Y V L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P67962 337 38882 Y213 S L G Y V L M Y F N R T S L P
Frog Xenopus laevis Q5BP74 415 47421 Y286 R Q G F S Y D Y V F D W N M L
Zebra Danio Brachydanio rerio Q7T2E3 403 46225 Y244 I E V L C K G Y P S E F A T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54367 337 39516 Y216 S L G Y V M M Y F N R G V L P
Honey Bee Apis mellifera XP_393612 350 40282 Y217 S L G Y V L M Y F N R G S L P
Nematode Worm Caenorhab. elegans P42168 341 39018 Y212 S L G Y V L M Y F N R G T L P
Sea Urchin Strong. purpuratus XP_786391 348 40003 Y227 S L G Y V L M Y F N R T S L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 Y244 I E A L C R G Y P S E F A S Y
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 H347 A M K K F P T H F H Y Y K N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.9 90.5 N.A. 54.5 88.1 N.A. N.A. 90.5 53.9 56.5 N.A. 70.6 76.2 75.3 74.1
Protein Similarity: 100 99.6 99.4 94.3 N.A. 66.1 91 N.A. N.A. 94.6 66 68.2 N.A. 81.3 84 82.1 84.2
P-Site Identity: 100 100 100 93.3 N.A. 13.3 13.3 N.A. N.A. 93.3 13.3 6.6 N.A. 80 86.6 80 93.3
P-Site Similarity: 100 100 100 93.3 N.A. 40 13.3 N.A. N.A. 93.3 40 20 N.A. 80 86.6 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 48.6 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 61.7 52.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 0 0 0 0 0 0 14 0 0 % A
% Cys: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 7 14 0 0 0 14 0 0 0 0 % D
% Glu: 0 14 0 0 0 0 0 7 0 0 14 0 0 0 7 % E
% Phe: 0 0 0 14 7 20 0 0 67 14 0 14 0 0 0 % F
% Gly: 0 0 74 0 0 0 14 0 0 0 7 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % H
% Ile: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 7 0 7 0 0 0 0 0 0 7 0 0 % K
% Leu: 0 60 0 14 0 34 0 0 0 7 0 0 0 67 14 % L
% Met: 0 7 0 0 0 7 67 0 0 0 0 0 0 14 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 60 0 0 14 7 0 % N
% Pro: 0 0 0 0 0 7 0 0 14 0 0 0 0 0 60 % P
% Gln: 7 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 14 0 7 7 0 7 0 0 0 0 60 0 0 0 0 % R
% Ser: 60 7 0 0 14 0 0 0 7 14 0 0 47 7 0 % S
% Thr: 0 0 0 0 0 0 7 0 0 0 0 40 7 7 0 % T
% Val: 0 0 7 0 60 0 0 0 14 0 0 0 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % W
% Tyr: 0 0 0 60 0 14 0 87 0 0 7 14 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _