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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1L
All Species:
32.42
Human Site:
Y175
Identified Species:
50.95
UniProt:
Q8N752
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N752
NP_660204.1
337
39086
Y175
R
T
R
Q
H
I
P
Y
R
E
D
K
H
L
I
Chimpanzee
Pan troglodytes
XP_522662
337
39019
Y175
R
T
R
Q
H
I
P
Y
R
E
D
K
H
L
I
Rhesus Macaque
Macaca mulatta
XP_001085343
337
38964
Y175
R
T
R
Q
H
I
P
Y
R
E
D
K
H
L
I
Dog
Lupus familis
XP_867638
336
38749
Y175
R
T
R
Q
H
I
P
Y
R
E
D
K
N
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
F248
C
K
G
Y
P
S
E
F
S
T
Y
L
N
F
C
Rat
Rattus norvegicus
P97633
325
37477
N167
L
A
K
K
Y
R
D
N
R
T
R
Q
H
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
Y175
R
T
R
Q
H
I
P
Y
R
E
D
K
N
L
T
Frog
Xenopus laevis
Q5BP74
415
47421
F248
C
K
G
Y
P
S
E
F
A
T
Y
L
N
F
C
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
F206
L
G
Y
V
L
M
Y
F
N
L
G
S
L
P
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
Y178
H
T
R
H
H
I
V
Y
R
E
D
K
N
L
T
Honey Bee
Apis mellifera
XP_393612
350
40282
Y179
R
T
R
M
H
I
M
Y
R
E
D
K
N
L
T
Nematode Worm
Caenorhab. elegans
P42168
341
39018
Y174
R
T
R
T
H
I
P
Y
R
E
D
K
N
L
T
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
Y189
R
S
K
Q
H
I
Q
Y
R
E
D
K
N
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
F206
L
G
Y
I
L
M
Y
F
L
K
G
S
L
P
W
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
E309
K
Q
R
D
L
L
I
E
K
G
D
L
N
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
90.5
N.A.
54.5
88.1
N.A.
N.A.
90.5
53.9
56.5
N.A.
70.6
76.2
75.3
74.1
Protein Similarity:
100
99.6
99.4
94.3
N.A.
66.1
91
N.A.
N.A.
94.6
66
68.2
N.A.
81.3
84
82.1
84.2
P-Site Identity:
100
100
100
86.6
N.A.
0
13.3
N.A.
N.A.
86.6
0
0
N.A.
66.6
73.3
80
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
46.6
N.A.
N.A.
93.3
13.3
13.3
N.A.
73.3
80
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.7
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% A
% Cys:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% C
% Asp:
0
0
0
7
0
0
7
0
0
0
67
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
14
7
0
60
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
27
0
0
0
0
0
14
0
% F
% Gly:
0
14
14
0
0
0
0
0
0
7
14
0
0
0
0
% G
% His:
7
0
0
7
60
0
0
0
0
0
0
0
27
0
0
% H
% Ile:
0
0
0
7
0
60
7
0
0
0
0
0
0
7
20
% I
% Lys:
7
14
14
7
0
0
0
0
7
7
0
60
0
0
0
% K
% Leu:
20
0
0
0
20
7
0
0
7
7
0
20
14
60
0
% L
% Met:
0
0
0
7
0
14
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
0
0
60
0
7
% N
% Pro:
0
0
0
0
14
0
40
0
0
0
0
0
0
14
7
% P
% Gln:
0
7
0
40
0
0
7
0
0
0
0
7
0
0
0
% Q
% Arg:
54
0
60
0
0
7
0
0
67
0
7
0
0
0
0
% R
% Ser:
0
7
0
0
0
14
0
0
7
0
0
14
0
0
0
% S
% Thr:
0
54
0
7
0
0
0
0
0
20
0
0
0
0
40
% T
% Val:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% W
% Tyr:
0
0
14
14
7
0
14
60
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _