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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1A1L All Species: 35.76
Human Site: Y126 Identified Species: 56.19
UniProt: Q8N752 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N752 NP_660204.1 337 39086 Y126 Q M I S R I E Y V H T K N F L
Chimpanzee Pan troglodytes XP_522662 337 39019 Y126 Q M I S R I E Y V H T K N F L
Rhesus Macaque Macaca mulatta XP_001085343 337 38964 Y126 Q M I S R I E Y V H T K N F L
Dog Lupus familis XP_867638 336 38749 Y126 Q M I S R I E Y V H T K N F I
Cat Felis silvestris
Mouse Mus musculus Q9JMK2 416 47304 K141 F L M G L G K K G N L V Y I I
Rat Rattus norvegicus P97633 325 37477 R123 L A D Q M I S R I E Y V H T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P67962 337 38882 Y126 Q M I S R I E Y V H T K N F I
Frog Xenopus laevis Q5BP74 415 47421 K141 F L M G L G K K G N L V Y I I
Zebra Danio Brachydanio rerio Q7T2E3 403 46225 K141 F L M G L G K K G N L V Y I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54367 337 39516 Y129 Q M I G R L E Y I H L K C F I
Honey Bee Apis mellifera XP_393612 350 40282 Y130 Q M I G R I E Y V H C K H F I
Nematode Worm Caenorhab. elegans P42168 341 39018 Y125 Q M I G R I E Y V H V K N F I
Sea Urchin Strong. purpuratus XP_786391 348 40003 Y140 Q M I A R I E Y V H V K N F I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 R141 F L M G L G R R A N Q V Y I I
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 S181 T G T A R Y A S V N T H L G I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.9 90.5 N.A. 54.5 88.1 N.A. N.A. 90.5 53.9 56.5 N.A. 70.6 76.2 75.3 74.1
Protein Similarity: 100 99.6 99.4 94.3 N.A. 66.1 91 N.A. N.A. 94.6 66 68.2 N.A. 81.3 84 82.1 84.2
P-Site Identity: 100 100 100 93.3 N.A. 0 6.6 N.A. N.A. 93.3 0 0 N.A. 60 73.3 80 80
P-Site Similarity: 100 100 100 100 N.A. 33.3 20 N.A. N.A. 100 33.3 33.3 N.A. 80 86.6 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 48.6 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 61.7 52.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 0 0 7 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 60 0 0 7 0 0 0 0 0 % E
% Phe: 27 0 0 0 0 0 0 0 0 0 0 0 0 60 0 % F
% Gly: 0 7 0 47 0 27 0 0 20 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 60 0 7 14 0 0 % H
% Ile: 0 0 60 0 0 60 0 0 14 0 0 0 0 27 74 % I
% Lys: 0 0 0 0 0 0 20 20 0 0 0 60 0 0 7 % K
% Leu: 7 27 0 0 27 7 0 0 0 0 27 0 7 0 20 % L
% Met: 0 60 27 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 34 0 0 47 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 60 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 0 0 67 0 7 14 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 34 0 0 7 7 0 0 0 0 0 0 0 % S
% Thr: 7 0 7 0 0 0 0 0 0 0 40 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 60 0 14 34 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 60 0 0 7 0 27 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _