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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1A1L All Species: 34.85
Human Site: T228 Identified Species: 54.76
UniProt: Q8N752 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N752 NP_660204.1 337 39086 T228 W Q G L R A M T K K Q K Y E K
Chimpanzee Pan troglodytes XP_522662 337 39019 T228 W Q G L R A M T K K Q K Y E K
Rhesus Macaque Macaca mulatta XP_001085343 337 38964 T228 W Q G L K A I T K K Q K Y E K
Dog Lupus familis XP_867638 336 38749 T228 W Q G L K A A T K K Q K Y E K
Cat Felis silvestris
Mouse Mus musculus Q9JMK2 416 47304 P301 K F G A A R N P E D V D R E R
Rat Rattus norvegicus P97633 325 37477 P220 Y F N R T S L P W Q G L K A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P67962 337 38882 T228 W Q G L K A A T K K Q K Y E K
Frog Xenopus laevis Q5BP74 415 47421 A301 K F G A S R A A E D A E R E R
Zebra Danio Brachydanio rerio Q7T2E3 403 46225 R259 L N F C R S L R F D D K P D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54367 337 39516 T231 W Q G M K A N T K Q Q K Y E K
Honey Bee Apis mellifera XP_393612 350 40282 T232 W Q G L K A A T K K Q K Y E K
Nematode Worm Caenorhab. elegans P42168 341 39018 T227 W Q G L K A A T K K Q K Y E K
Sea Urchin Strong. purpuratus XP_786391 348 40003 T242 W Q G M K A M T K K Q K Y E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 R259 F H Y C R S L R F D D K P D Y
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 E362 D K H N P S P E E I K Q Q T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.9 90.5 N.A. 54.5 88.1 N.A. N.A. 90.5 53.9 56.5 N.A. 70.6 76.2 75.3 74.1
Protein Similarity: 100 99.6 99.4 94.3 N.A. 66.1 91 N.A. N.A. 94.6 66 68.2 N.A. 81.3 84 82.1 84.2
P-Site Identity: 100 100 86.6 86.6 N.A. 13.3 0 N.A. N.A. 86.6 13.3 13.3 N.A. 73.3 86.6 86.6 86.6
P-Site Similarity: 100 100 100 93.3 N.A. 26.6 26.6 N.A. N.A. 93.3 33.3 33.3 N.A. 93.3 93.3 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. 48.6 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 61.7 52.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 7 60 34 7 0 0 7 0 0 7 7 % A
% Cys: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 27 14 7 0 14 0 % D
% Glu: 0 0 0 0 0 0 0 7 20 0 0 7 0 74 0 % E
% Phe: 7 20 7 0 0 0 0 0 14 0 0 0 0 0 0 % F
% Gly: 0 0 74 0 0 0 0 0 0 0 7 0 0 0 0 % G
% His: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 7 % I
% Lys: 14 7 0 0 47 0 0 0 60 54 7 74 7 0 60 % K
% Leu: 7 0 0 47 0 0 20 0 0 0 0 7 0 0 0 % L
% Met: 0 0 0 14 0 0 20 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 7 0 0 14 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 7 0 7 14 0 0 0 0 14 0 0 % P
% Gln: 0 60 0 0 0 0 0 0 0 14 60 7 7 0 0 % Q
% Arg: 0 0 0 7 27 14 0 14 0 0 0 0 14 0 14 % R
% Ser: 0 0 0 0 7 27 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 0 0 60 0 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % V
% Trp: 60 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 7 0 7 0 0 0 0 0 0 0 0 0 60 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _