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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1A1L All Species: 37.88
Human Site: T112 Identified Species: 59.52
UniProt: Q8N752 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N752 NP_660204.1 337 39086 T112 S R R F T M K T V L M L A D Q
Chimpanzee Pan troglodytes XP_522662 337 39019 T112 S R R F T M K T V L M L A D Q
Rhesus Macaque Macaca mulatta XP_001085343 337 38964 T112 S R R F T M K T V L M L A D Q
Dog Lupus familis XP_867638 336 38749 T112 S R R F T M K T V L M L A D Q
Cat Felis silvestris
Mouse Mus musculus Q9JMK2 416 47304 R127 H S K N F I H R D V K P D N F
Rat Rattus norvegicus P97633 325 37477 T109 N F C S R R F T M K T V L M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P67962 337 38882 T112 S R R F T M K T V L M L A D Q
Frog Xenopus laevis Q5BP74 415 47421 R127 H S K N F I H R D V K P D N F
Zebra Danio Brachydanio rerio Q7T2E3 403 46225 R127 H S K N F I H R D V K P D N F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54367 337 39516 T115 T R H F T I K T V L M L V D Q
Honey Bee Apis mellifera XP_393612 350 40282 T116 T R R F T I K T V L M L A D Q
Nematode Worm Caenorhab. elegans P42168 341 39018 T111 S R R F T M K T V L M L A D Q
Sea Urchin Strong. purpuratus XP_786391 348 40003 T126 S R K F T M K T V L M L A D Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 R127 H S K S F L H R D L K P D N F
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 Y167 N T H R H I P Y R E N K S L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.9 90.5 N.A. 54.5 88.1 N.A. N.A. 90.5 53.9 56.5 N.A. 70.6 76.2 75.3 74.1
Protein Similarity: 100 99.6 99.4 94.3 N.A. 66.1 91 N.A. N.A. 94.6 66 68.2 N.A. 81.3 84 82.1 84.2
P-Site Identity: 100 100 100 100 N.A. 0 6.6 N.A. N.A. 100 0 0 N.A. 73.3 86.6 100 93.3
P-Site Similarity: 100 100 100 100 N.A. 26.6 26.6 N.A. N.A. 100 26.6 26.6 N.A. 86.6 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. 48.6 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 61.7 52.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 54 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 27 0 0 0 27 60 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % E
% Phe: 0 7 0 60 27 0 7 0 0 0 0 0 0 0 27 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 27 0 14 0 7 0 27 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 34 0 0 0 60 0 0 7 27 7 0 0 0 % K
% Leu: 0 0 0 0 0 7 0 0 0 67 0 60 7 7 7 % L
% Met: 0 0 0 0 0 47 0 0 7 0 60 0 0 7 0 % M
% Asn: 14 0 0 20 0 0 0 0 0 0 7 0 0 27 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 27 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % Q
% Arg: 0 60 47 7 7 7 0 27 7 0 0 0 0 0 0 % R
% Ser: 47 27 0 14 0 0 0 0 0 0 0 0 7 0 0 % S
% Thr: 14 7 0 0 60 0 0 67 0 0 7 0 0 0 7 % T
% Val: 0 0 0 0 0 0 0 0 60 20 0 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _