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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USHBP1 All Species: 13.64
Human Site: S274 Identified Species: 33.33
UniProt: Q8N6Y0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N6Y0 NP_114147.2 703 76068 S274 R R L R S H S S T Q I L G S L
Chimpanzee Pan troglodytes XP_001173333 703 75994 G274 R R L H S H S G T Q I L G S L
Rhesus Macaque Macaca mulatta XP_001113384 703 76174 S274 R R L R S H S S T Q I L G S L
Dog Lupus familis XP_541958 703 76090 S274 R R L R S D S S T Q M L G P L
Cat Felis silvestris
Mouse Mus musculus Q8R370 680 74812 T264 R L R S D S S T Q S F G C L S
Rat Rattus norvegicus Q3T1I3 680 74593 T264 R L R S D S S T Q S F G C L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514875 829 91014 S272 R R A R S C S S A Q L L G H L
Chicken Gallus gallus XP_413971 825 92902 R334 R V K L S K T R S E S S S S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921192 502 56563 H181 E A D S S A L H M A L A Y C E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786141 903 100683 P370 Q S A Q N V N P S T G E L S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 94.1 75.6 N.A. 58.7 60.3 N.A. 33.9 25 N.A. 21.3 N.A. N.A. N.A. N.A. 22.9
Protein Similarity: 100 98.2 96.3 82.3 N.A. 69.2 70.6 N.A. 47 42.7 N.A. 36.5 N.A. N.A. N.A. N.A. 38.6
P-Site Identity: 100 86.6 100 80 N.A. 13.3 13.3 N.A. 66.6 20 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 86.6 100 86.6 N.A. 20 20 N.A. 73.3 40 N.A. 13.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 20 0 0 10 0 0 10 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 20 10 0 % C
% Asp: 0 0 10 0 20 10 0 0 0 0 0 0 0 0 10 % D
% Glu: 10 0 0 0 0 0 0 0 0 10 0 10 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 10 20 50 0 0 % G
% His: 0 0 0 10 0 30 0 10 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 % I
% Lys: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 20 40 10 0 0 10 0 0 0 20 50 10 20 60 % L
% Met: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % P
% Gln: 10 0 0 10 0 0 0 0 20 50 0 0 0 0 0 % Q
% Arg: 80 50 20 40 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 30 70 20 70 40 20 20 10 10 10 50 20 % S
% Thr: 0 0 0 0 0 0 10 20 40 10 0 0 0 0 0 % T
% Val: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _