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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRAM1
All Species:
20.61
Human Site:
Y197
Identified Species:
50.37
UniProt:
Q8N682
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N682
NP_060840.2
238
26253
Y197
P
R
E
K
D
Y
V
Y
H
V
V
S
A
I
C
Chimpanzee
Pan troglodytes
XP_001155525
207
22482
V166
I
R
M
V
I
S
A
V
S
C
A
A
V
I
P
Rhesus Macaque
Macaca mulatta
XP_001093215
238
26193
Y197
P
R
E
K
D
Y
V
Y
H
V
V
S
A
I
C
Dog
Lupus familis
XP_855009
238
26083
Y197
P
K
E
K
D
Y
V
Y
H
V
V
S
A
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC58
238
26182
Y197
P
K
E
K
D
Y
I
Y
H
V
V
S
A
I
C
Rat
Rattus norvegicus
Q5BK09
267
30154
L204
P
E
D
K
G
Y
V
L
H
I
V
T
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507139
220
24252
N179
P
D
E
K
D
Y
K
N
H
L
G
S
A
I
C
Chicken
Gallus gallus
XP_001234899
238
26433
Y197
P
S
E
K
D
Y
T
Y
H
F
M
S
A
I
C
Frog
Xenopus laevis
Q6NRS6
239
26604
Y198
P
S
D
E
G
Y
P
Y
H
L
T
S
A
I
C
Zebra Danio
Brachydanio rerio
Q32PK2
232
25997
F190
E
W
I
L
V
M
C
F
F
A
L
F
G
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
98.3
93.6
N.A.
94.5
39.7
N.A.
70.1
71
61.9
23.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
99.5
95.8
N.A.
97.4
58
N.A.
80.2
81.9
78.2
43.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
86.6
40
N.A.
66.6
73.3
53.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
60
N.A.
73.3
80
73.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
10
10
70
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
70
% C
% Asp:
0
10
20
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
60
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
10
10
0
10
0
0
10
% F
% Gly:
0
0
0
0
20
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
10
0
10
0
0
10
0
0
0
80
0
% I
% Lys:
0
20
0
70
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
10
0
20
10
0
0
0
0
% L
% Met:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
80
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
0
10
0
0
10
0
0
70
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
10
10
10
0
0
% T
% Val:
0
0
0
10
10
0
40
10
0
40
50
0
10
10
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
80
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _