KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MS4A15
All Species:
11.52
Human Site:
Y172
Identified Species:
42.22
UniProt:
Q8N5U1
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5U1
NP_001092305.1
240
25050
Y172
N
R
D
V
D
R
G
Y
L
A
V
L
T
I
F
Chimpanzee
Pan troglodytes
XP_001140063
267
28132
W194
G
V
A
G
Q
D
Y
W
A
V
L
S
G
K
G
Rhesus Macaque
Macaca mulatta
XP_001085764
288
30168
Y218
N
W
D
V
D
R
G
Y
L
A
V
L
A
I
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3UPL6
245
25923
Y175
N
W
D
V
G
R
G
Y
L
A
V
L
T
I
F
Rat
Rattus norvegicus
P13386
243
26712
K163
S
A
Y
M
N
Y
C
K
D
I
T
E
D
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505375
242
25610
Y172
N
W
D
V
G
R
G
Y
L
A
V
L
V
I
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923190
248
26984
I169
H
W
N
I
F
L
R
I
S
G
V
L
L
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
74.3
N.A.
N.A.
78.7
28.3
N.A.
71.4
N.A.
N.A.
34.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.5
77
N.A.
N.A.
82.8
47.3
N.A.
84.7
N.A.
N.A.
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
N.A.
N.A.
86.6
0
N.A.
80
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
86.6
N.A.
N.A.
86.6
20
N.A.
80
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
0
0
0
0
0
15
58
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
58
0
29
15
0
0
15
0
0
0
15
15
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
72
% F
% Gly:
15
0
0
15
29
0
58
0
0
15
0
0
15
0
29
% G
% His:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
15
0
15
0
0
0
58
0
% I
% Lys:
0
0
0
0
0
0
0
15
0
0
0
0
0
15
0
% K
% Leu:
0
0
0
0
0
15
0
0
58
0
15
72
15
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
58
0
15
0
15
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
58
15
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
15
0
29
0
0
% T
% Val:
0
15
0
58
0
0
0
0
0
15
72
0
15
15
0
% V
% Trp:
0
58
0
0
0
0
0
15
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
15
15
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _