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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A41
All Species:
11.21
Human Site:
S281
Identified Species:
18.97
UniProt:
Q8N5S1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5S1
NP_775908.2
370
40795
S281
G
R
D
M
G
D
P
S
G
L
V
S
L
S
S
Chimpanzee
Pan troglodytes
XP_524070
370
40707
S281
G
T
D
M
G
D
P
S
G
L
V
S
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001088055
515
57586
P421
Y
S
H
D
S
A
D
P
G
I
L
V
L
L
A
Dog
Lupus familis
XP_542139
368
40383
S279
G
R
D
M
E
D
P
S
G
L
V
S
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVN7
312
34487
T227
L
V
S
L
S
S
V
T
L
S
T
T
C
G
Q
Rat
Rattus norvegicus
Q8K3P6
469
52677
G376
A
V
N
S
A
D
P
G
V
F
V
L
L
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519699
472
53241
P378
Y
S
Q
N
S
A
D
P
G
I
L
V
L
L
A
Chicken
Gallus gallus
XP_001233165
491
54684
G398
A
V
N
S
A
D
P
G
V
F
V
L
L
A
C
Frog
Xenopus laevis
Q7T0U6
473
52371
P382
H
A
K
D
S
A
N
P
G
V
L
V
L
L
G
Zebra Danio
Brachydanio rerio
Q66L49
477
53337
P384
Y
A
K
D
T
A
N
P
G
V
L
V
L
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19529
531
59257
G436
Y
T
E
H
T
E
P
G
V
L
A
L
L
A
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P29518
436
46609
D323
T
G
R
R
P
G
A
D
V
G
P
V
A
T
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65023
381
41798
S280
Y
R
K
K
A
Q
S
S
L
L
T
A
V
L
S
Baker's Yeast
Sacchar. cerevisiae
P48233
545
61252
P446
Q
A
K
T
L
N
L
P
Q
D
Q
V
T
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
43.8
88.9
N.A.
72.4
40.2
N.A.
45.9
40.3
43.7
38.7
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
100
98.3
54.1
92.9
N.A.
77.5
54.3
N.A.
58
52.7
56
54.2
N.A.
N.A.
N.A.
47.6
N.A.
P-Site Identity:
100
93.3
13.3
93.3
N.A.
0
26.6
N.A.
13.3
26.6
13.3
13.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
93.3
33.3
93.3
N.A.
20
40
N.A.
33.3
40
26.6
26.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
27.2
N.A.
25.7
24.2
N.A.
Protein Similarity:
N.A.
44.9
N.A.
45.4
40.3
N.A.
P-Site Identity:
N.A.
0
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
22
0
0
22
29
8
0
0
0
8
8
8
22
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
22
% C
% Asp:
0
0
22
22
0
36
15
8
0
8
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% F
% Gly:
22
8
0
0
15
8
0
22
50
8
0
0
0
8
15
% G
% His:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% I
% Lys:
0
0
29
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
8
0
8
0
15
36
29
22
72
43
8
% L
% Met:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
8
0
8
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
43
36
0
0
8
0
0
0
0
% P
% Gln:
8
0
8
0
0
8
0
0
8
0
8
0
0
0
8
% Q
% Arg:
0
22
8
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
8
15
29
8
8
29
0
8
0
22
0
22
36
% S
% Thr:
8
15
0
8
15
0
0
8
0
0
15
8
8
8
0
% T
% Val:
0
22
0
0
0
0
8
0
29
15
36
43
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
36
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _