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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFAP1
All Species:
22.12
Human Site:
S124
Identified Species:
69.52
UniProt:
Q8N556
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N556
NP_001128119.1
730
80725
S124
A
M
S
S
S
Y
E
S
Y
D
E
E
E
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092605
814
91012
E146
E
A
V
S
S
S
Y
E
S
Y
D
E
E
D
G
Dog
Lupus familis
XP_545904
857
94535
S124
A
M
S
S
S
Y
E
S
Y
D
E
E
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80YS6
731
80596
S123
A
M
S
S
S
Y
E
S
Y
D
E
E
E
E
D
Rat
Rattus norvegicus
Q8VH46
731
80733
S123
A
M
G
S
S
Y
E
S
Y
D
E
E
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90738
729
81141
S124
A
M
S
S
S
Y
E
S
Y
D
E
E
E
E
D
Frog
Xenopus laevis
Q6PF55
811
90890
S151
A
V
S
S
S
Y
E
S
Y
D
E
D
E
S
N
Zebra Danio
Brachydanio rerio
Q4V8Y7
746
84147
G152
P
P
N
S
I
E
D
G
Y
Y
E
D
A
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
33.9
78.1
N.A.
91.9
90.8
N.A.
N.A.
87.9
36.6
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
50.6
81.5
N.A.
95.3
94.6
N.A.
N.A.
92.8
54.5
61.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
26.6
100
N.A.
100
93.3
N.A.
N.A.
100
73.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
40
100
N.A.
100
93.3
N.A.
N.A.
100
93.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
75
13
25
0
13
63
% D
% Glu:
13
0
0
0
0
13
75
13
0
0
88
75
88
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
0
13
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
25
% N
% Pro:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
63
100
88
13
0
75
13
0
0
0
0
13
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
75
13
0
88
25
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _