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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AFAP1L2 All Species: 21.82
Human Site: S208 Identified Species: 53.33
UniProt: Q8N4X5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4X5 NP_001001936.1 818 91300 S208 N R L L C Y K S S K D H S P Q
Chimpanzee Pan troglodytes XP_001150419 817 91217 S208 N R L M C Y K S S K D H S P Q
Rhesus Macaque Macaca mulatta XP_001092605 814 91012 S208 N R L L C Y K S S K D H S P Q
Dog Lupus familis XP_544028 1006 111817 S388 T R L L C Y K S S K D H S P Q
Cat Felis silvestris
Mouse Mus musculus Q5DTU0 825 92156 S208 T R L L C Y K S S K D H S P Q
Rat Rattus norvegicus Q8VH46 731 80733 D152 A S M D L V K D A K I C A F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513664 759 85321 P174 E H K L K I T P L N A D V I V
Chicken Gallus gallus Q90738 729 81141 L150 S E E A S M D L V K D A K I C
Frog Xenopus laevis Q6PF55 811 90890 T214 T R L M C Y K T S K D H N P Q
Zebra Danio Brachydanio rerio Q4V8Y7 746 84147 N167 N Y P T T Q V N G R R K N S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.9 69.9 N.A. 82.6 34.1 N.A. 67.3 33.7 57.4 35 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 98.7 73.4 N.A. 89.4 49.6 N.A. 76.6 51.7 72.9 51.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 93.3 N.A. 93.3 13.3 N.A. 6.6 13.3 73.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 33.3 N.A. 6.6 20 93.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 0 10 0 10 10 10 0 0 % A
% Cys: 0 0 0 0 60 0 0 0 0 0 0 10 0 0 10 % C
% Asp: 0 0 0 10 0 0 10 10 0 0 70 10 0 0 0 % D
% Glu: 10 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 60 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 10 0 0 20 0 % I
% Lys: 0 0 10 0 10 0 70 0 0 80 0 10 10 0 0 % K
% Leu: 0 0 60 50 10 0 0 10 10 0 0 0 0 0 10 % L
% Met: 0 0 10 20 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 40 0 0 0 0 0 0 10 0 10 0 0 20 0 0 % N
% Pro: 0 0 10 0 0 0 0 10 0 0 0 0 0 60 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 60 % Q
% Arg: 0 60 0 0 0 0 0 0 0 10 10 0 0 0 0 % R
% Ser: 10 10 0 0 10 0 0 50 60 0 0 0 50 10 0 % S
% Thr: 30 0 0 10 10 0 10 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 10 0 10 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 60 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _