KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDDC3
All Species:
24.55
Human Site:
T134
Identified Species:
54
UniProt:
Q8N4P3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4P3
NP_940929.1
179
20329
T134
L
R
D
L
N
R
C
T
P
E
G
W
S
E
H
Chimpanzee
Pan troglodytes
XP_001170043
143
15938
R102
L
P
K
L
E
R
K
R
L
Q
V
E
Q
A
P
Rhesus Macaque
Macaca mulatta
XP_001093163
179
20312
T134
L
R
D
L
N
R
C
T
P
E
G
W
S
E
H
Dog
Lupus familis
XP_545862
179
20256
T134
L
R
D
L
N
R
C
T
P
E
G
W
S
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D114
179
20243
T134
L
R
D
L
N
R
C
T
P
T
G
W
S
E
H
Rat
Rattus norvegicus
NP_001100998
179
20235
T134
L
R
D
L
N
R
C
T
P
K
G
W
S
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q568P1
180
20277
T135
L
R
D
L
N
R
C
T
P
E
G
W
S
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651682
179
20551
T135
L
R
D
L
Q
V
N
T
P
T
G
W
T
Q
E
Honey Bee
Apis mellifera
XP_624961
220
25452
I163
L
R
D
L
Q
E
N
I
P
V
G
W
S
Q
D
Nematode Worm
Caenorhab. elegans
NP_493608
229
26788
A186
L
R
D
L
E
R
K
A
P
I
G
W
D
K
K
Sea Urchin
Strong. purpuratus
XP_784835
179
20443
I132
L
R
D
L
D
Q
E
I
P
R
G
W
T
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.7
98.8
93.8
N.A.
95.5
94.9
N.A.
N.A.
N.A.
N.A.
72.2
N.A.
58
45
44.9
60.3
Protein Similarity:
100
79.8
100
95.5
N.A.
97.7
98.8
N.A.
N.A.
N.A.
N.A.
81.6
N.A.
70.9
57.7
54.5
79.3
P-Site Identity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
53.3
53.3
53.3
46.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
66.6
60
60
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
91
0
10
0
0
0
0
0
0
0
10
0
10
% D
% Glu:
0
0
0
0
19
10
10
0
0
37
0
10
0
46
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
37
% H
% Ile:
0
0
0
0
0
0
0
19
0
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
19
0
0
10
0
0
0
19
10
% K
% Leu:
100
0
0
100
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
55
0
19
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
91
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
19
10
0
0
0
10
0
0
10
19
10
% Q
% Arg:
0
91
0
0
0
73
0
10
0
10
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% S
% Thr:
0
0
0
0
0
0
0
64
0
19
0
0
19
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _