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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf41
All Species:
34.55
Human Site:
Y254
Identified Species:
58.46
UniProt:
Q8N4J0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4J0
NP_689633.1
409
47186
Y254
E
I
N
K
Y
K
L
Y
P
W
I
H
Q
F
S
Chimpanzee
Pan troglodytes
XP_528328
475
54088
Y320
E
I
N
K
Y
K
L
Y
P
W
I
H
Q
F
S
Rhesus Macaque
Macaca mulatta
XP_001094584
599
67458
Y445
E
I
N
K
Y
K
L
Y
P
W
I
H
Q
F
S
Dog
Lupus familis
XP_533523
411
47217
Y256
E
I
N
K
Y
K
L
Y
P
W
I
H
Q
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80UY1
400
46320
Y245
E
I
N
K
Y
K
L
Y
P
W
I
H
Q
F
S
Rat
Rattus norvegicus
Q5BJZ6
400
46366
Y245
E
V
D
K
Y
K
L
Y
P
W
I
H
Q
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506791
344
39296
V197
E
R
W
D
T
S
K
V
N
I
L
V
P
G
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089556
373
43795
Y217
E
I
N
A
F
K
I
Y
P
W
I
H
Q
F
S
Zebra Danio
Brachydanio rerio
NP_001013361
303
34889
S156
P
Q
S
L
P
E
D
S
D
F
S
M
V
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7X6
439
50486
Y224
N
E
N
K
Y
V
L
Y
P
W
V
H
Q
Y
V
Honey Bee
Apis mellifera
XP_623835
380
44379
F223
E
H
Q
T
Q
A
V
F
F
P
D
V
N
P
S
Nematode Worm
Caenorhab. elegans
NP_496829
369
42995
D222
N
N
S
W
N
Y
S
D
Q
L
R
P
V
T
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307920
281
31851
S135
N
C
N
S
L
S
D
S
D
Q
L
R
P
V
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_180775
449
51403
Y284
L
P
G
E
W
T
I
Y
P
W
I
H
T
N
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.1
67.7
97.3
N.A.
90.7
90.4
N.A.
65.2
N.A.
69.6
49.3
N.A.
39.1
45.4
35.2
N.A.
Protein Similarity:
100
86.1
67.9
98
N.A.
93.4
93.1
N.A.
70.4
N.A.
79.7
58.9
N.A.
54.9
62.8
54.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
6.6
N.A.
80
0
N.A.
60
13.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
N.A.
93.3
20
N.A.
73.3
26.6
6.6
N.A.
Percent
Protein Identity:
33.9
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
48.6
N.A.
N.A.
51.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
8
8
0
0
15
8
15
0
8
0
0
0
0
% D
% Glu:
65
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
8
8
8
0
0
0
50
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
65
0
0
0
% H
% Ile:
0
43
0
0
0
0
15
0
0
8
58
0
0
0
0
% I
% Lys:
0
0
0
50
0
50
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
8
0
50
0
0
8
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
22
8
58
0
8
0
0
0
8
0
0
0
8
8
0
% N
% Pro:
8
8
0
0
8
0
0
0
65
8
0
8
15
8
0
% P
% Gln:
0
8
8
0
8
0
0
0
8
8
0
0
58
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% R
% Ser:
0
0
15
8
0
15
8
15
0
0
8
0
0
0
65
% S
% Thr:
0
0
0
8
8
8
0
0
0
0
0
0
8
8
0
% T
% Val:
0
8
0
0
0
8
8
8
0
0
8
15
15
8
8
% V
% Trp:
0
0
8
8
8
0
0
0
0
65
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
8
0
65
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _