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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARL14
All Species:
15.45
Human Site:
T185
Identified Species:
20
UniProt:
Q8N4G2
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4G2
NP_079323.1
192
21622
T185
H
M
K
S
R
G
D
T
L
A
F
F
K
Q
N
Chimpanzee
Pan troglodytes
XP_526367
192
21571
T185
H
M
K
S
R
G
D
T
L
A
F
F
K
Q
N
Rhesus Macaque
Macaca mulatta
XP_001096998
192
21591
T185
H
M
K
S
R
G
D
T
L
A
F
F
K
Q
N
Dog
Lupus familis
XP_545258
192
21648
A185
H
M
K
S
R
G
D
A
L
A
F
F
K
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3SXC5
192
21817
Rat
Rattus norvegicus
P84079
181
20678
S174
Y
E
G
L
D
W
L
S
N
Q
L
R
N
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519240
189
21531
F175
G
F
R
K
I
T
G
F
V
K
S
H
R
E
E
Chicken
Gallus gallus
P26990
175
20078
W168
G
L
Y
E
G
L
T
W
L
T
S
N
Y
K
S
Frog
Xenopus laevis
P51645
175
20169
W168
G
L
Y
E
G
L
T
W
L
T
S
N
Y
K
S
Zebra Danio
Brachydanio rerio
NP_001093453
201
22603
K186
T
P
D
D
N
N
I
K
E
T
V
K
Y
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40946
175
19987
W168
G
L
S
E
G
L
I
W
L
T
S
N
H
K
L
Honey Bee
Apis mellifera
XP_393787
180
20403
Nematode Worm
Caenorhab. elegans
Q10943
181
20503
S174
Y
E
G
L
D
W
L
S
N
Q
L
K
N
R
S
Sea Urchin
Strong. purpuratus
XP_787374
185
21005
W175
G
L
Y
E
G
L
D
W
L
A
N
I
L
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49076
181
20642
S174
Y
E
G
L
D
W
L
S
S
N
I
A
T
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P36397
181
20590
S174
Y
E
G
L
D
W
L
S
N
N
I
A
S
K
A
Baker's Yeast
Sacchar. cerevisiae
P11076
181
20511
S174
Y
E
G
L
E
W
L
S
N
S
L
K
N
S
T
Red Bread Mold
Neurospora crassa
Q7RVM2
185
20961
S177
F
E
G
L
D
W
L
S
T
E
L
K
K
K
S
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.4
N.A.
75
41.6
N.A.
67.7
40
39
50.7
N.A.
41.6
43.7
41.1
43.2
Protein Similarity:
100
99.4
98.9
95.3
N.A.
90
66.6
N.A.
83.3
65
64.5
71.1
N.A.
64
67.1
68.2
66.6
P-Site Identity:
100
100
100
93.3
N.A.
0
6.6
N.A.
0
6.6
6.6
0
N.A.
6.6
0
0
20
P-Site Similarity:
100
100
100
93.3
N.A.
0
20
N.A.
26.6
26.6
26.6
0
N.A.
20
0
26.6
33.3
Percent
Protein Identity:
N.A.
42.1
N.A.
42.7
40.6
41.6
Protein Similarity:
N.A.
66.1
N.A.
66.1
66.1
66.6
P-Site Identity:
N.A.
0
N.A.
0
0
6.6
P-Site Similarity:
N.A.
26.6
N.A.
20
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
6
0
28
0
12
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
6
28
0
28
0
0
0
0
0
0
0
0
% D
% Glu:
0
34
0
23
6
0
0
0
6
6
0
0
0
6
6
% E
% Phe:
6
6
0
0
0
0
0
6
0
0
23
23
0
0
0
% F
% Gly:
28
0
34
0
23
23
6
0
0
0
0
0
0
0
6
% G
% His:
23
0
0
0
0
0
0
0
0
0
0
6
6
0
0
% H
% Ile:
0
0
0
0
6
0
12
0
0
0
12
6
0
6
0
% I
% Lys:
0
0
23
6
0
0
0
6
0
6
0
23
28
39
6
% K
% Leu:
0
23
0
34
0
23
34
0
45
0
23
0
6
0
6
% L
% Met:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
6
6
0
0
23
12
6
17
17
0
23
% N
% Pro:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
0
0
28
0
% Q
% Arg:
0
0
6
0
23
0
0
0
0
0
0
6
6
6
6
% R
% Ser:
0
0
6
23
0
0
0
34
6
6
23
0
6
6
28
% S
% Thr:
6
0
0
0
0
6
12
17
6
23
0
0
6
0
6
% T
% Val:
0
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
34
0
23
0
0
0
0
0
0
0
% W
% Tyr:
28
0
17
0
0
0
0
0
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _