KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
D2HGDH
All Species:
9.7
Human Site:
T42
Identified Species:
15.24
UniProt:
Q8N465
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N465
NP_689996.4
521
56416
T42
G
C
C
S
A
P
G
T
P
E
V
P
L
T
R
Chimpanzee
Pan troglodytes
XP_001162772
466
50496
P27
A
A
G
S
W
G
R
P
V
G
P
L
A
R
R
Rhesus Macaque
Macaca mulatta
XP_001094865
519
56150
T40
G
C
C
S
A
P
G
T
P
E
V
P
L
T
R
Dog
Lupus familis
XP_852029
541
59008
G62
S
S
S
T
P
A
S
G
P
E
V
A
L
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIM3
535
58556
G56
A
Y
S
V
V
A
G
G
P
E
V
T
L
T
P
Rat
Rattus norvegicus
P84850
535
58786
S56
A
Y
S
K
V
S
G
S
P
E
V
M
L
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422664
541
59236
C62
L
H
T
A
R
P
R
C
Q
E
V
P
L
T
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L258
533
58696
R53
R
D
V
H
N
S
R
R
L
G
A
N
P
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V778
631
70803
G76
G
E
K
Y
P
L
G
G
C
E
L
P
S
F
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45218
597
66541
I68
W
F
E
N
Y
L
G
I
D
L
G
F
V
S
P
Sea Urchin
Strong. purpuratus
XP_783292
557
61383
S76
S
R
H
L
Y
G
A
S
S
D
V
P
L
T
R
Poplar Tree
Populus trichocarpa
XP_002310828
530
58306
L47
N
G
G
R
N
P
Q
L
Y
R
S
F
G
S
L
Maize
Zea mays
NP_001141496
562
61260
Q79
A
N
K
A
C
E
V
Q
K
R
T
F
G
S
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23240
559
61427
S65
E
L
H
H
P
C
I
S
R
N
V
G
M
L
L
Baker's Yeast
Sacchar. cerevisiae
P46681
530
59250
Q41
N
Y
Y
S
T
K
I
Q
T
R
L
T
S
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85
95.5
78.9
N.A.
79.4
79.6
N.A.
N.A.
68.7
N.A.
61.7
N.A.
21.2
N.A.
20.4
53.5
Protein Similarity:
100
86.9
97.1
86.1
N.A.
86.7
87.2
N.A.
N.A.
81.1
N.A.
76.3
N.A.
37
N.A.
38.3
67.8
P-Site Identity:
100
13.3
100
33.3
N.A.
40
40
N.A.
N.A.
40
N.A.
0
N.A.
26.6
N.A.
6.6
33.3
P-Site Similarity:
100
13.3
100
46.6
N.A.
40
46.6
N.A.
N.A.
46.6
N.A.
0
N.A.
33.3
N.A.
26.6
46.6
Percent
Protein Identity:
52.2
50.8
N.A.
50.8
50.3
N.A.
Protein Similarity:
68.6
65.8
N.A.
65.6
66.6
N.A.
P-Site Identity:
6.6
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
13.3
13.3
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
7
0
14
14
14
7
0
0
0
7
7
7
7
7
% A
% Cys:
0
14
14
0
7
7
0
7
7
0
0
0
0
0
7
% C
% Asp:
0
7
0
0
0
0
0
0
7
7
0
0
0
0
0
% D
% Glu:
7
7
7
0
0
7
0
0
0
47
0
0
0
7
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
20
0
7
0
% F
% Gly:
20
7
14
0
0
14
40
20
0
14
7
7
14
0
0
% G
% His:
0
7
14
14
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
14
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
14
7
0
7
0
0
7
0
0
0
0
0
0
% K
% Leu:
7
7
0
7
0
14
0
7
7
7
14
7
47
7
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% M
% Asn:
14
7
0
7
14
0
0
0
0
7
0
7
0
0
14
% N
% Pro:
0
0
0
0
20
27
0
7
34
0
7
34
7
0
20
% P
% Gln:
0
0
0
0
0
0
7
14
7
0
0
0
0
0
7
% Q
% Arg:
7
7
0
7
7
0
20
7
7
20
0
0
0
7
27
% R
% Ser:
14
7
20
27
0
14
7
20
7
0
7
0
14
20
0
% S
% Thr:
0
0
7
7
7
0
0
14
7
0
7
14
0
47
7
% T
% Val:
0
0
7
7
14
0
7
0
7
0
54
0
7
0
0
% V
% Trp:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
7
7
14
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _