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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
D2HGDH
All Species:
4.85
Human Site:
S23
Identified Species:
7.62
UniProt:
Q8N465
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N465
NP_689996.4
521
56416
S23
G
A
P
G
A
A
G
S
W
G
R
P
V
G
P
Chimpanzee
Pan troglodytes
XP_001162772
466
50496
A8
M
L
P
R
R
P
L
A
W
P
A
W
L
L
R
Rhesus Macaque
Macaca mulatta
XP_001094865
519
56150
S21
F
R
P
G
A
A
G
S
W
G
R
P
V
G
P
Dog
Lupus familis
XP_852029
541
59008
G43
P
R
P
L
G
P
W
G
A
V
G
N
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIM3
535
58556
C37
V
G
L
K
R
L
G
C
P
R
G
V
Y
S
P
Rat
Rattus norvegicus
P84850
535
58786
C37
A
Q
L
K
W
L
G
C
P
R
S
V
Y
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422664
541
59236
A43
E
R
R
R
P
C
R
A
A
V
T
P
W
L
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L258
533
58696
P34
A
V
T
A
R
E
T
P
D
R
A
L
I
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V778
631
70803
Q57
G
W
G
Y
N
D
S
Q
F
Y
G
K
D
G
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45218
597
66541
E49
T
F
T
G
D
K
Y
E
I
S
G
K
V
M
P
Sea Urchin
Strong. purpuratus
XP_783292
557
61383
A57
S
V
K
A
T
C
R
A
S
N
H
Q
V
R
R
Poplar Tree
Populus trichocarpa
XP_002310828
530
58306
P28
R
Q
L
T
S
N
N
P
I
Y
R
S
I
S
A
Maize
Zea mays
NP_001141496
562
61260
T60
Q
H
P
L
C
G
P
T
S
S
G
G
I
Y
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23240
559
61427
K46
N
H
Y
K
S
K
G
K
L
F
E
L
S
D
G
Baker's Yeast
Sacchar. cerevisiae
P46681
530
59250
K22
K
F
A
G
R
Y
M
K
S
S
A
L
L
G
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85
95.5
78.9
N.A.
79.4
79.6
N.A.
N.A.
68.7
N.A.
61.7
N.A.
21.2
N.A.
20.4
53.5
Protein Similarity:
100
86.9
97.1
86.1
N.A.
86.7
87.2
N.A.
N.A.
81.1
N.A.
76.3
N.A.
37
N.A.
38.3
67.8
P-Site Identity:
100
13.3
86.6
13.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
0
N.A.
13.3
N.A.
20
6.6
P-Site Similarity:
100
26.6
86.6
13.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
N.A.
6.6
N.A.
20
N.A.
20
13.3
Percent
Protein Identity:
52.2
50.8
N.A.
50.8
50.3
N.A.
Protein Similarity:
68.6
65.8
N.A.
65.6
66.6
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
20
20
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
14
14
14
0
20
14
0
20
0
0
0
7
% A
% Cys:
0
0
0
0
7
14
0
14
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
7
7
0
0
7
0
0
0
7
7
0
% D
% Glu:
7
0
0
0
0
7
0
7
0
0
7
0
0
0
7
% E
% Phe:
7
14
0
0
0
0
0
0
7
7
0
0
0
0
0
% F
% Gly:
14
7
7
27
7
7
34
7
0
14
34
7
0
27
7
% G
% His:
0
14
0
0
0
0
0
0
0
0
7
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
14
0
0
0
20
0
7
% I
% Lys:
7
0
7
20
0
14
0
14
0
0
0
14
0
0
0
% K
% Leu:
0
7
20
14
0
14
7
0
7
0
0
20
14
14
0
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% M
% Asn:
7
0
0
0
7
7
7
0
0
7
0
7
0
0
0
% N
% Pro:
7
0
34
0
7
14
7
14
14
7
0
20
0
7
40
% P
% Gln:
7
14
0
0
0
0
0
7
0
0
0
7
0
0
0
% Q
% Arg:
7
20
7
14
27
0
14
0
0
20
20
0
0
7
14
% R
% Ser:
7
0
0
0
14
0
7
14
20
20
7
7
14
20
0
% S
% Thr:
7
0
14
7
7
0
7
7
0
0
7
0
0
0
0
% T
% Val:
7
14
0
0
0
0
0
0
0
14
0
14
27
7
0
% V
% Trp:
0
7
0
0
7
0
7
0
20
0
0
7
7
0
0
% W
% Tyr:
0
0
7
7
0
7
7
0
0
14
0
0
14
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _