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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1C
All Species:
28.18
Human Site:
Y148
Identified Species:
56.36
UniProt:
Q8N431
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N431
NP_778232.2
466
52870
Y148
I
A
P
C
D
E
A
Y
R
K
R
M
H
Q
L
Chimpanzee
Pan troglodytes
XP_518156
546
61226
Y228
I
A
P
C
D
E
A
Y
R
K
R
M
H
Q
L
Rhesus Macaque
Macaca mulatta
XP_001102791
466
52809
Y148
I
A
P
C
D
E
A
Y
R
K
R
M
H
Q
L
Dog
Lupus familis
XP_538583
684
76123
Y213
I
A
P
C
D
E
A
Y
R
K
R
M
H
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D300
466
52705
Y148
I
S
P
C
D
E
T
Y
G
S
R
V
H
Q
L
Rat
Rattus norvegicus
NP_001101743
466
52800
Y148
I
S
P
C
D
E
T
Y
G
N
R
M
H
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
V199
C
D
E
E
N
G
T
V
K
K
I
I
S
Q
M
Chicken
Gallus gallus
XP_414615
480
55173
Y157
I
A
P
C
D
E
A
Y
W
K
K
M
N
Q
L
Frog
Xenopus laevis
NP_001086251
419
48694
F117
V
L
S
T
R
G
Q
F
Q
E
V
R
E
K
I
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
Y190
L
S
T
G
E
D
L
Y
R
K
A
V
Q
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396254
713
79278
A398
V
A
A
V
D
A
A
A
R
Q
E
V
S
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
L280
C
I
A
I
D
P
T
L
R
K
S
A
G
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
98
63
N.A.
94.6
94.8
N.A.
51.3
81
50.4
62.8
N.A.
N.A.
37.3
N.A.
44.4
Protein Similarity:
100
85.1
98.9
66.2
N.A.
97.4
97.4
N.A.
66
87.9
65.4
73.9
N.A.
N.A.
48.3
N.A.
56.8
P-Site Identity:
100
100
100
100
N.A.
66.6
73.3
N.A.
13.3
80
0
26.6
N.A.
N.A.
33.3
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
40
93.3
40
66.6
N.A.
N.A.
53.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
17
0
0
9
50
9
0
0
9
9
0
9
0
% A
% Cys:
17
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
75
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
9
9
59
0
0
0
9
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
17
0
0
17
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% H
% Ile:
59
9
0
9
0
0
0
0
0
0
9
9
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
9
67
9
0
0
9
0
% K
% Leu:
9
9
0
0
0
0
9
9
0
0
0
0
0
0
75
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
17
% M
% Asn:
0
0
0
0
9
0
0
0
0
9
0
0
9
0
0
% N
% Pro:
0
0
59
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
9
9
0
0
9
84
0
% Q
% Arg:
0
0
0
0
9
0
0
0
59
0
50
9
0
0
0
% R
% Ser:
0
25
9
0
0
0
0
0
0
9
9
0
17
0
0
% S
% Thr:
0
0
9
9
0
0
34
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
9
0
0
0
9
0
0
9
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _