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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1C
All Species:
22.73
Human Site:
T184
Identified Species:
45.45
UniProt:
Q8N431
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N431
NP_778232.2
466
52870
T184
D
K
P
I
S
Y
R
T
K
P
P
A
S
I
H
Chimpanzee
Pan troglodytes
XP_518156
546
61226
T264
D
K
P
I
S
Y
R
T
K
P
P
A
S
I
H
Rhesus Macaque
Macaca mulatta
XP_001102791
466
52809
T184
D
K
P
I
S
Y
K
T
K
P
P
A
S
I
H
Dog
Lupus familis
XP_538583
684
76123
T251
D
K
P
I
S
Y
R
T
K
P
P
A
S
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D300
466
52705
T184
D
K
P
I
S
Y
R
T
K
P
P
A
S
I
H
Rat
Rattus norvegicus
NP_001101743
466
52800
T184
D
K
P
I
S
Y
R
T
K
P
P
A
S
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
K239
V
D
K
G
T
I
L
K
A
K
P
Q
A
P
Q
Chicken
Gallus gallus
XP_414615
480
55173
K197
S
D
K
L
V
A
F
K
S
K
P
P
S
I
Q
Frog
Xenopus laevis
NP_001086251
419
48694
K136
S
D
K
G
T
I
L
K
T
K
P
Q
S
A
Q
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
K230
T
D
R
L
T
V
L
K
T
K
P
Q
S
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396254
713
79278
G438
T
T
E
Q
L
P
N
G
T
V
N
R
V
F
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
R320
S
E
R
M
H
A
L
R
A
N
P
A
S
F
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
98
63
N.A.
94.6
94.8
N.A.
51.3
81
50.4
62.8
N.A.
N.A.
37.3
N.A.
44.4
Protein Similarity:
100
85.1
98.9
66.2
N.A.
97.4
97.4
N.A.
66
87.9
65.4
73.9
N.A.
N.A.
48.3
N.A.
56.8
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
6.6
20
13.3
20
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
26.6
20
33.3
N.A.
N.A.
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
17
0
0
59
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
17
0
% F
% Gly:
0
0
0
17
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
50
% H
% Ile:
0
0
0
50
0
17
0
0
0
0
0
0
0
67
0
% I
% Lys:
0
50
25
0
0
0
9
34
50
34
0
0
0
0
0
% K
% Leu:
0
0
0
17
9
0
34
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
9
9
0
0
0
0
% N
% Pro:
0
0
50
0
0
9
0
0
0
50
92
9
0
9
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
25
0
0
50
% Q
% Arg:
0
0
17
0
0
0
42
9
0
0
0
9
0
0
0
% R
% Ser:
25
0
0
0
50
0
0
0
9
0
0
0
84
0
0
% S
% Thr:
17
9
0
0
25
0
0
50
25
0
0
0
0
0
0
% T
% Val:
9
0
0
0
9
9
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _