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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1C
All Species:
22.42
Human Site:
S6
Identified Species:
44.85
UniProt:
Q8N431
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N431
NP_778232.2
466
52870
S6
_
_
M
P
Q
T
L
S
A
S
D
M
V
T
P
Chimpanzee
Pan troglodytes
XP_518156
546
61226
S86
A
D
M
P
Q
T
L
S
A
S
D
M
V
T
P
Rhesus Macaque
Macaca mulatta
XP_001102791
466
52809
S6
_
_
M
P
Q
T
L
S
A
S
D
M
V
T
P
Dog
Lupus familis
XP_538583
684
76123
N71
T
G
M
P
R
T
L
N
T
S
D
M
V
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D300
466
52705
T6
_
_
M
P
R
T
L
T
A
S
D
M
V
T
P
Rat
Rattus norvegicus
NP_001101743
466
52800
T6
_
_
M
P
R
T
L
T
A
S
D
M
V
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
I54
E
T
M
P
Q
T
P
I
F
S
S
M
L
G
S
Chicken
Gallus gallus
XP_414615
480
55173
S15
E
G
M
P
Q
T
L
S
S
T
S
M
F
T
P
Frog
Xenopus laevis
NP_001086251
419
48694
L11
T
Y
I
F
T
F
L
L
S
A
R
I
F
I
H
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
F48
K
M
P
Q
T
P
P
F
P
V
M
Y
G
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396254
713
79278
S257
S
G
S
A
G
T
G
S
G
M
V
N
G
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
R138
V
T
T
G
D
V
S
R
K
C
N
G
L
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
98
63
N.A.
94.6
94.8
N.A.
51.3
81
50.4
62.8
N.A.
N.A.
37.3
N.A.
44.4
Protein Similarity:
100
85.1
98.9
66.2
N.A.
97.4
97.4
N.A.
66
87.9
65.4
73.9
N.A.
N.A.
48.3
N.A.
56.8
P-Site Identity:
100
86.6
100
66.6
N.A.
84.6
84.6
N.A.
40
60
6.6
0
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
86.6
100
86.6
N.A.
100
100
N.A.
46.6
80
40
6.6
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
0
42
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
0
50
0
0
0
0
% D
% Glu:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
9
0
9
9
0
0
0
17
0
0
% F
% Gly:
0
25
0
9
9
0
9
0
9
0
0
9
17
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
0
0
9
0
0
0
0
9
0
0
0
9
0
9
0
% I
% Lys:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
67
9
0
0
0
0
17
0
0
% L
% Met:
0
9
67
0
0
0
0
0
0
9
9
67
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
9
0
0
0
% N
% Pro:
0
0
9
67
0
9
17
0
9
0
0
0
0
0
59
% P
% Gln:
0
0
0
9
42
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
25
0
0
9
0
0
9
0
0
0
0
% R
% Ser:
9
0
9
0
0
0
9
42
17
59
17
0
0
17
9
% S
% Thr:
17
17
9
0
17
75
0
17
9
9
0
0
0
59
9
% T
% Val:
9
0
0
0
0
9
0
0
0
9
9
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
34
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% _