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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1C
All Species:
22.73
Human Site:
S445
Identified Species:
45.45
UniProt:
Q8N431
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N431
NP_778232.2
466
52870
S445
L
A
S
Y
E
S
E
S
P
E
N
Q
T
E
K
Chimpanzee
Pan troglodytes
XP_518156
546
61226
S525
L
A
S
Y
E
S
E
S
P
E
N
Q
T
E
K
Rhesus Macaque
Macaca mulatta
XP_001102791
466
52809
S445
L
A
S
Y
E
S
E
S
P
E
N
Q
T
E
K
Dog
Lupus familis
XP_538583
684
76123
Q512
L
A
M
E
G
N
V
Q
L
D
T
G
N
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D300
466
52705
S445
L
A
S
Y
E
S
E
S
P
E
S
Q
T
E
K
Rat
Rattus norvegicus
NP_001101743
466
52800
S445
L
A
S
Y
E
S
E
S
P
E
N
Q
T
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
G501
V
A
S
F
E
S
E
G
P
E
N
H
M
E
K
Chicken
Gallus gallus
XP_414615
480
55173
S459
L
A
S
Y
E
S
E
S
P
E
N
Q
T
E
K
Frog
Xenopus laevis
NP_001086251
419
48694
G398
L
A
S
F
E
N
E
G
P
D
N
H
M
E
K
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
G493
L
A
S
Y
E
S
E
G
P
E
N
N
M
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396254
713
79278
P683
I
A
F
L
Q
A
R
P
V
W
T
E
N
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
P568
L
N
Y
L
L
T
A
P
V
F
S
E
N
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
98
63
N.A.
94.6
94.8
N.A.
51.3
81
50.4
62.8
N.A.
N.A.
37.3
N.A.
44.4
Protein Similarity:
100
85.1
98.9
66.2
N.A.
97.4
97.4
N.A.
66
87.9
65.4
73.9
N.A.
N.A.
48.3
N.A.
56.8
P-Site Identity:
100
100
100
13.3
N.A.
93.3
100
N.A.
66.6
100
60
80
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
80
100
80
80
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
92
0
0
0
9
9
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
9
75
0
75
0
0
67
0
17
0
75
0
% E
% Phe:
0
0
9
17
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
25
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% K
% Leu:
84
0
0
17
9
0
0
0
9
0
0
0
0
0
17
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
0
9
0
0
0
17
0
0
0
0
67
9
25
9
0
% N
% Pro:
0
0
0
0
0
0
0
17
75
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
9
0
0
0
50
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
75
0
0
67
0
50
0
0
17
0
0
9
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
17
0
50
0
9
% T
% Val:
9
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
9
59
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _