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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1C
All Species:
14.85
Human Site:
S236
Identified Species:
29.7
UniProt:
Q8N431
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N431
NP_778232.2
466
52870
S236
V
N
K
D
P
L
A
S
T
K
P
C
F
S
D
Chimpanzee
Pan troglodytes
XP_518156
546
61226
S316
V
N
K
D
P
L
A
S
T
K
P
C
F
S
D
Rhesus Macaque
Macaca mulatta
XP_001102791
466
52809
S236
V
N
K
D
P
L
A
S
T
K
P
C
F
S
D
Dog
Lupus familis
XP_538583
684
76123
S303
V
N
K
D
P
L
A
S
T
K
P
C
F
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D300
466
52705
G236
V
N
K
D
P
L
A
G
T
K
P
R
F
S
D
Rat
Rattus norvegicus
NP_001101743
466
52800
G236
V
N
K
D
P
L
A
G
T
K
P
R
F
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
H292
H
M
D
S
L
D
N
H
K
C
R
G
D
V
T
Chicken
Gallus gallus
XP_414615
480
55173
T250
H
K
D
P
L
D
G
T
K
P
C
F
S
D
Q
Frog
Xenopus laevis
NP_001086251
419
48694
H189
H
M
D
S
L
D
N
H
K
C
R
S
D
V
T
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
K284
K
D
P
L
D
N
D
K
N
C
F
S
D
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396254
713
79278
E490
A
K
E
S
P
H
L
E
T
S
F
K
D
M
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
T374
Q
N
D
G
D
G
Q
T
V
K
F
Q
D
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
98
63
N.A.
94.6
94.8
N.A.
51.3
81
50.4
62.8
N.A.
N.A.
37.3
N.A.
44.4
Protein Similarity:
100
85.1
98.9
66.2
N.A.
97.4
97.4
N.A.
66
87.9
65.4
73.9
N.A.
N.A.
48.3
N.A.
56.8
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
0
0
0
0
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
0
6.6
0
6.6
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
25
9
34
0
0
0
% C
% Asp:
0
9
34
50
17
25
9
0
0
0
0
0
42
9
42
% D
% Glu:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
25
9
50
0
0
% F
% Gly:
0
0
0
9
0
9
9
17
0
0
0
9
0
0
0
% G
% His:
25
0
0
0
0
9
0
17
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
17
50
0
0
0
0
9
25
59
0
9
0
0
25
% K
% Leu:
0
0
0
9
25
50
9
0
0
0
0
0
0
9
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
59
0
0
0
9
17
0
9
0
0
0
0
9
0
% N
% Pro:
0
0
9
9
59
0
0
0
0
9
50
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
9
0
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
17
17
0
0
0
% R
% Ser:
0
0
0
25
0
0
0
34
0
9
0
17
9
42
0
% S
% Thr:
0
0
0
0
0
0
0
17
59
0
0
0
0
0
17
% T
% Val:
50
0
0
0
0
0
0
0
9
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _