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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS35
All Species:
18.79
Human Site:
Y336
Identified Species:
51.67
UniProt:
Q8N3Z0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3Z0
NP_699193.1
413
47098
Y336
D
E
S
N
D
L
L
Y
Q
Y
C
D
A
E
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q1WK24
409
46494
Y332
D
E
S
N
D
L
L
Y
Q
Y
C
D
A
E
S
Dog
Lupus familis
XP_539023
357
40123
E286
L
Y
Q
Y
C
D
A
E
S
G
S
T
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0F9
409
45768
Y334
S
N
D
L
L
Y
Q
Y
C
D
A
E
A
G
S
Rat
Rattus norvegicus
Q5R212
406
45477
Y331
S
N
D
L
L
Y
Q
Y
C
D
A
E
A
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512903
412
47052
Y335
D
E
S
S
D
L
F
Y
Q
Y
C
D
A
A
P
Chicken
Gallus gallus
XP_419860
413
46849
Y336
D
E
S
N
D
L
F
Y
Q
Y
C
D
A
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002212
418
47252
Y341
E
E
S
N
D
L
L
Y
Q
Y
C
D
A
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796599
311
35578
G240
L
F
Y
Q
Q
C
D
G
D
S
D
A
V
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.9
N.A.
77.2
78.6
N.A.
73.6
70.2
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
100
N.A.
96.3
84
N.A.
85.7
86.4
N.A.
84
83.2
N.A.
70.8
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
N.A.
100
0
N.A.
20
20
N.A.
73.3
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
100
0
N.A.
26.6
26.6
N.A.
80
86.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
23
12
78
12
12
% A
% Cys:
0
0
0
0
12
12
0
0
23
0
56
0
0
0
0
% C
% Asp:
45
0
23
0
56
12
12
0
12
23
12
56
0
0
0
% D
% Glu:
12
56
0
0
0
0
0
12
0
0
0
23
0
34
0
% E
% Phe:
0
12
0
0
0
0
23
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
12
0
0
12
34
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
23
0
0
23
23
56
34
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
23
0
45
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% P
% Gln:
0
0
12
12
12
0
23
0
56
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
23
0
56
12
0
0
0
0
12
12
12
0
0
12
45
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
12
0
23
0
78
0
56
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _