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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS35
All Species:
8.48
Human Site:
S236
Identified Species:
23.33
UniProt:
Q8N3Z0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3Z0
NP_699193.1
413
47098
S236
G
G
R
R
R
K
K
S
G
R
G
Q
R
I
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q1WK24
409
46494
S232
A
G
R
R
R
K
Q
S
G
G
G
Q
R
V
S
Dog
Lupus familis
XP_539023
357
40123
V186
E
S
G
R
G
Q
R
V
A
E
G
R
P
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0F9
409
45768
R234
R
P
G
K
K
S
R
R
G
P
R
V
T
Q
G
Rat
Rattus norvegicus
Q5R212
406
45477
R231
R
P
G
K
K
S
R
R
G
P
R
V
A
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512903
412
47052
I235
G
R
R
K
K
D
S
I
Q
G
H
H
R
V
V
Chicken
Gallus gallus
XP_419860
413
46849
S236
G
G
R
K
Q
R
R
S
G
R
K
Q
G
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002212
418
47252
N241
S
K
G
K
G
R
R
N
R
S
R
R
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796599
311
35578
T140
L
K
P
E
E
I
S
T
D
E
W
E
K
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.9
N.A.
77.2
78.6
N.A.
73.6
70.2
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
100
N.A.
96.3
84
N.A.
85.7
86.4
N.A.
84
83.2
N.A.
70.8
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
N.A.
66.6
13.3
N.A.
6.6
6.6
N.A.
20
46.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
86.6
33.3
N.A.
26.6
26.6
N.A.
40
80
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
12
0
0
0
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
12
% D
% Glu:
12
0
0
12
12
0
0
0
0
23
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
34
34
45
0
23
0
0
0
56
23
34
0
12
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
12
0
0
0
0
0
12
0
% I
% Lys:
0
23
0
56
34
23
12
0
0
0
12
0
12
0
0
% K
% Leu:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
23
12
0
0
0
0
0
0
23
0
0
12
0
0
% P
% Gln:
0
0
0
0
12
12
12
0
12
0
0
34
0
23
0
% Q
% Arg:
23
12
45
34
23
23
56
23
12
23
34
23
34
0
0
% R
% Ser:
12
12
0
0
0
23
23
34
0
12
0
0
12
23
23
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
12
12
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
23
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _