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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP8
All Species:
18.18
Human Site:
S289
Identified Species:
44.44
UniProt:
Q8N3A8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3A8
NP_078891.2
854
95871
S289
L
F
S
T
L
R
R
S
P
S
Y
P
P
P
G
Chimpanzee
Pan troglodytes
XP_001151176
833
93349
I290
L
K
S
E
Q
D
G
I
S
K
T
H
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001093952
854
95810
S289
L
F
S
T
L
R
R
S
P
S
Y
P
P
P
G
Dog
Lupus familis
XP_853766
852
95417
S287
L
F
S
T
L
R
R
S
P
S
Y
P
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UD82
852
95541
R288
H
L
F
S
T
L
R
R
S
P
S
Y
P
P
P
Rat
Rattus norvegicus
XP_001068789
852
95545
R288
H
L
F
S
T
L
R
R
S
P
S
Y
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514099
907
100542
S340
I
F
S
T
L
R
R
S
P
S
Y
P
P
P
G
Chicken
Gallus gallus
XP_424786
876
98087
S309
I
F
S
T
L
R
R
S
P
S
Y
P
P
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070643
859
96370
P288
F
S
T
L
R
R
S
P
S
Y
P
P
P
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783307
627
70977
Q88
G
D
I
D
I
D
L
Q
L
D
V
S
F
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.8
97.3
N.A.
96.1
96.5
N.A.
82.3
85.7
N.A.
80.2
N.A.
N.A.
N.A.
N.A.
38.2
Protein Similarity:
100
97
99.1
98.8
N.A.
97.7
97.7
N.A.
85.8
89.7
N.A.
88.5
N.A.
N.A.
N.A.
N.A.
52.4
P-Site Identity:
100
13.3
100
100
N.A.
20
20
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
26.6
26.6
N.A.
100
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
10
0
20
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
50
20
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
0
0
0
0
10
50
% G
% His:
20
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
20
0
10
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% K
% Leu:
40
20
0
10
50
20
10
0
10
0
0
0
0
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
50
20
10
60
80
70
20
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
10
60
70
20
0
0
0
0
0
0
0
% R
% Ser:
0
10
60
20
0
0
10
50
40
50
20
10
0
0
0
% S
% Thr:
0
0
10
50
20
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
50
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _