KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC43
All Species:
4.24
Human Site:
S474
Identified Species:
15.56
UniProt:
Q8N309
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N309
NP_001091989.1
656
73022
S474
C
S
Y
E
M
Q
H
S
L
R
D
L
V
P
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094455
591
65228
N453
S
P
G
T
V
L
F
N
T
T
H
K
P
W
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3V0L5
667
74923
T498
C
T
Y
E
M
K
H
T
L
K
E
L
I
R
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506374
578
64015
K443
S
P
P
G
K
K
G
K
K
N
Q
E
K
K
E
Chicken
Gallus gallus
XP_415151
600
66559
D457
T
K
G
P
G
P
R
D
K
Q
K
K
K
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P45969
326
37341
Q191
L
E
G
V
E
T
L
Q
K
L
S
V
L
S
L
Sea Urchin
Strong. purpuratus
XP_789973
642
70965
A460
D
K
A
K
D
A
K
A
A
K
D
D
G
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81.5
N.A.
N.A.
67
N.A.
N.A.
51.9
43.9
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
26.8
Protein Similarity:
100
N.A.
84.5
N.A.
N.A.
79.3
N.A.
N.A.
65.8
59.2
N.A.
N.A.
N.A.
N.A.
N.A.
32.3
43.9
P-Site Identity:
100
N.A.
0
N.A.
N.A.
46.6
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
13.3
N.A.
N.A.
93.3
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
15
0
15
15
0
0
0
0
0
15
% A
% Cys:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
15
0
0
15
0
0
29
15
0
0
0
% D
% Glu:
0
15
0
29
15
0
0
0
0
0
15
15
0
0
15
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
43
15
15
0
15
0
0
0
0
0
15
0
0
% G
% His:
0
0
0
0
0
0
29
0
0
0
15
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% I
% Lys:
0
29
0
15
15
29
15
15
43
29
15
29
29
43
29
% K
% Leu:
15
0
0
0
0
15
15
0
29
15
0
29
15
0
29
% L
% Met:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
15
0
0
0
0
0
% N
% Pro:
0
29
15
15
0
15
0
0
0
0
0
0
15
15
0
% P
% Gln:
0
0
0
0
0
15
0
15
0
15
15
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
15
0
0
15
0
0
0
15
0
% R
% Ser:
29
15
0
0
0
0
0
15
0
0
15
0
0
15
0
% S
% Thr:
15
15
0
15
0
15
0
15
15
15
0
0
0
0
0
% T
% Val:
0
0
0
15
15
0
0
0
0
0
0
15
15
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% W
% Tyr:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _