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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGGF1
All Species:
24.24
Human Site:
S353
Identified Species:
48.48
UniProt:
Q8N302
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N302
NP_060516.2
714
80977
S353
L
H
E
N
I
S
N
S
T
S
F
K
D
E
K
Chimpanzee
Pan troglodytes
XP_526886
714
80982
S353
L
H
E
N
I
S
N
S
T
S
F
K
D
E
K
Rhesus Macaque
Macaca mulatta
XP_001106588
710
80468
S349
L
H
E
D
I
S
N
S
T
S
F
K
D
E
K
Dog
Lupus familis
XP_536317
711
80206
S350
L
N
E
S
I
Y
N
S
T
S
F
K
D
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN31
711
79427
S350
E
S
P
G
D
D
N
S
A
S
S
K
D
E
R
Rat
Rattus norvegicus
XP_001060407
705
79061
S343
E
S
P
G
V
E
A
S
A
S
L
K
D
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513838
745
83514
T384
L
N
V
S
V
Y
N
T
A
L
Y
K
D
D
K
Chicken
Gallus gallus
XP_414679
690
77765
T339
D
D
N
R
I
V
D
T
E
S
E
P
E
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073451
774
87501
R402
T
K
K
K
R
A
L
R
D
R
K
S
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611023
601
66926
L276
N
D
A
E
E
G
E
L
S
Q
S
S
D
S
S
Honey Bee
Apis mellifera
XP_394532
554
62863
R229
K
K
R
K
L
A
K
R
E
G
Q
S
E
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783785
1289
142207
S564
P
D
V
I
V
I
D
S
D
D
S
D
M
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
96.9
88.8
N.A.
78
78
N.A.
65.3
60.5
N.A.
43.7
N.A.
27.1
27.5
N.A.
23.5
Protein Similarity:
100
99.4
97.7
92.3
N.A.
88
86.5
N.A.
75.9
73.1
N.A.
60.3
N.A.
43.8
46
N.A.
37.5
P-Site Identity:
100
100
93.3
80
N.A.
40
33.3
N.A.
33.3
20
N.A.
0
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
46.6
N.A.
73.3
40
N.A.
13.3
N.A.
13.3
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
17
9
0
25
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
25
0
9
9
9
17
0
17
9
0
9
67
17
9
% D
% Glu:
17
0
34
9
9
9
9
0
17
0
9
0
17
67
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% F
% Gly:
0
0
0
17
0
9
0
0
0
9
0
0
9
0
9
% G
% His:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
42
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
17
9
17
0
0
9
0
0
0
9
59
0
0
42
% K
% Leu:
42
0
0
0
9
0
9
9
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
17
9
17
0
0
50
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
17
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
0
9
9
9
0
0
17
0
9
0
0
0
0
17
% R
% Ser:
0
17
0
17
0
25
0
59
9
59
25
25
0
17
9
% S
% Thr:
9
0
0
0
0
0
0
17
34
0
0
0
0
0
0
% T
% Val:
0
0
17
0
25
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _